February 5th, 2025

A new paper describes Nicole's  research on the function of the histone methyltransferase DOT1B in       L. mexicana.

February 3^rd, 2025

Expansion microscopy, BioID, TrypTag and Alphafold joined forces to produce this new map of the trypansosome nuclear pore complex, which is an update to the fantastic work that Sam Obado published in 2016.

January, 2nd, 2025

Excited to share the results of our fruitful collaboration with Eva Gluenz and Andreia Albuquerque-Wendt, now published in Nature Communications! It's great to see this work finally out.

December 16th, 2024

A new paper describes Nadine's research on the composition of telomer-binding protein complexes in T. brucei.

Nov 7th, 2024

Johanna and Bernardo presented fantastic science at a great meeting in Caxambu. Bernardo won the Walter Colli Prize for the best talk. Many congratulations!

October, 29th, 2024

Many congratulations to Stephan on successfully defending his PhD thesis.

October 11th, 2024

Bernardo wins the 1st prize of the Speaker Award for presenting his brand-new story on the trypanosome nuclear pore complex. Well done and many congratulations!

Oct 8th, 2024

We are expanding (the knowledge) of the trypanosome nuclear pore: have a look!

August, 29th, 2024

Our Paper about visualisation of difficult and/or low-abundant proteins with TurboID got accepted in eLife!

April 15th, 2024

Fabian's fantastic work on trypanosome endosomes published!

March 19th, 2024

Nadine defended her PhD thesis on telomere-associated proteins. We are so proud of you!!!

March 14th, 2024

New paper derived form a fruitful collaboration with Hiroki Shibuya’s lab in Gothenburg/Sweden on AdipoR2 function in meiotic telomere and chromosome dynamics

February 14th, 2024

My sweet valentine! Many congratulations to Fabian on successfully defending his PhD thesis.

December 2nd, 2023

Try out streptavidin-imaging, AI-audio-summarized here !

November 23rd, 2023

Laura Hauf's and Chris Reuter's Paper on tsetse-transmission of trypansomes to advanced skin models is published! Congratulations!

October 17th, 2023

Alyssa successfully defended her PhD thesis on the endo-lysosomal system of Trypanosoma brucei. Many congratulations!

October 4th -6th, 2023

We are hosting the 2nd workshop of the EU-ITN PHYMOT, a 3-day international meeting celebrating the movement of microbes

September 27th, 2023

The brand new Dr. Jamie Lisack with her PhD advisory commitee consisting of Markus Engstler and Alvaro Acosta-Serrano from the University of Notre Dame, USA and Philip Kollmannsberger from the HHU Düsseldorf.

September 27th, 2023

The newest addition to the Engstler lab alumni. Congratulations!

September 19th, 2023

Open PhD position in the Kramer lab! If you like to work as part of an international team on the unique Kinetoplastida mRNA decapping enzyme, please apply to Susanne Kramer. More details on the project are here.

July 18th, 2023

Nico Ankenbrand (left) and Daniel Bardolf (right) successfully completed their BTA training. Congratulations! We wish them all the best for their future careers!

June 13th, 2023

Check out on its friends!

June 1st, 2023

Dr Eli Meiser is the latest graduate of the Fenz Lab. Very well done Eli!!

May 24h, 2023

Check out Tom's new method for gene editing and scalable functional genomic screening in Leishmania species.

24^th February 2023

"SUN4 is a spermatid type II inner nuclear membrane protein that forms heteromeric assemblies with SUN3 and interacts with lamin B3"

December 8th, 2022

Tom Beneke developed a CRISPR/Cas9 cytosine base editor toolbox for Leishmania that enables for the first time functional genetic screens via delivery of plasmid libraries. Check it out!

November, 23, 2022

It depends ... read Claudias Paper to find out. And Happy Birthday Claudia!

20^th October 2022

Markus Engstler receives the Memento Research Prize in Berlin

October 6th, 2022

Fabian Link won the prize for the best talk. Congratulations!

September, 13-17, 2022

Seven of us presented at the Kinetoplastid Molecular Cell Biology Meeting (KMCBM IX) in Woods Hole (MA, USA)

30th August 2022

... the Kramer lab would not exist without you.

RIP

July, 30th, 2022

A great scientist and truly great human being has left us. We will never forget you. Rest in peace, Paul.

July 20th, 2022

Congratulations on successfully completing the biology laboratory assistant training!

Our TrypClub speaker on Thursday 9th June will be Dr. Smita Sutrave from the Bundesinstitut für Risikobewertung.

"The German Federal Institute for Risk Assessment: at a glance"

(March 16th, 2022)

A characterisation of the TbSmee1 protein, with intriguing observations on cargo entry into trypanosomes.

Fun fact: 100% of the data for this preprint were obtained by undergraduates!

May 18, 2022 -- A103, 03:30 p.m.

Prof. Daniel Chourrout (Sars Centre, University of Bergen, Norway)

"Genomic Turbulence near Vertebrates"

December 8th, 2021

Chris has already graduated in December. Time to put this in the news ;-)

April 14th, 2022

Hanna's work on Sun4 topology and interactions is now posted on the preprint server

April 1st, 2022

Five new researchers in our department: Franziska Schönhofer (B.A., Jones-Engstler), Nashmil Aslam (PhD, Jones-Engstler), Antonia Konle (PhD, Morriswood), Tom Beneke (Postdoc, Engstler) and Jose Carlos Quilles (Postdoc, Kramer).

March 25th, 2022

A new paper derived from a fruitful collaboration with our colleagues from the physiological chemistry and the human genetics departments

March 25th, 2022

This is Major Tom to Ground Control
I'm stepping through the door
And I'm floating in a most peculiar way
And the stars look very different today

March 24-25th, 2022

Inaugural meeting of the DFG priority programme 2332 held via Zoom.

March 1st, 2022

Joint statement of DVGeo, DPG, GDCh and VBIO concerning the war in Ukraine

February 21st, 2022

Spot the new doctor! Many congratulations!

January 10th, 2022

Uli Scheer hat die spannende Geschichte der Zoologie in Würzburg recherchiert. Wirklich sehr lesenswert!

November 9th, 2021

Nicole discovered an unexpected interaction between DOT1B and the Ribonuclease H2 protein complex. She opened the door to a new project with fantastic collaborators.

November 2nd, 2021

The results of our brilliant collaboration with the labs of Erec Stebbins and Nina Papavasiliou at DKFZ Heidelberg have been published. Well done to Alexander Hempelmann at DKFZ Heidelberg, Laura Hartleb and Kevin Bongers (ZEB Würzburg) and everyone else involved!

November 1st, 2021

The glycosylphosphatidylinositol (GPI) anchor: a linchpin for cell surface versatility of trypanosomatids

August 6th, 2021

We wanted to know what the VSG 16mer does and ended with the DExD/H protein Hel66. That's science ;-)

August 6th, 2021

Finally! Our paper on the life cycle of Trypanosoma brucei is published. It was a long struggle against dogmatic unbelief. 

August 6th, 2021

To the surface and back – exo- and endocytic pathways in Trypanosoma brucei

July 2nd, 2011

Ten years ago, our dear colleague Norbert Wilken passed away. We have not forgotten him!

June 29th, 2021

We show that many ApaH like phosphatases can decap mRNAs in vitro. But only Kinetoplastids actually USE the enzyme for mRNA decapping in vivo. They are special! (We always knew this)

June 25th, 2021

Congratulations on successfully defending your PhD thesis, Erick! Very well done!

June 22nd, 2021

Very suprisingly, we have data showing that the active ES is also transcriptionally attenuated

May 12th, 2021

Majeed's work on the DExD/H protein Hel66  is is on the preprint server. Congrats!

May 14th, 2021

Chris Reuter's opus magnum is finished!

May 5th, 2021

Erick's work on mRNA-balancing is out. Read it!

May, 5th 2021

We are ALL negative. Lisa can go to the beer garden soon, without testing, but she wont taste the beer :-(

April, 14th, 2021

Many congratulations Carina! Well done!

April 8th, 2021

Single cell motility in trypanosome 2D collectives.

April 7th, 2021

The identification of a SWR1 complex provides insights into transcriptional regulation in T. brucei

March 24th, 2021

New review from the Kramer lab

January 15th, 2021

Great collaboration with Erec Stebbins et al. and some real surprises on the trypanosome surface.

December 19th, 2020

Why is it, that only trypanosomes use extraterrestrical (ok, bacterial) proteins for mRNA decapping?

December 10th, 2020

New paper from the Morriswood group, with high-resolution structures of the MORN1 protein from Trypanosoma brucei, Toxoplasma gondii, Plasmodium falciparum.

Dec 4th, 2020

October 5th, 2020

Nicole Eisenhuth defends her PhD thesis on the histone methyl-transferase DOT1B in Trypanosoma brucei (and Leishmania).

October 5th, 2020

A fruitful collaboration with Markus Sauer’s lab published in Nature Communications

October 5th, 2020

Irene da Cruz’ work on the evolutionary history of meiotic telomere anchoring to the nuclear envelope

October 5th, 2020

Human infertility, meiosis and the synaptonemal complex

October 2nd, 2020

Markus Engstler elected vice-president of VBIO

September 25th, 2020

Marie-Christin Spindler defends her thesis on the molecular organization of the meiotic nucleus. Amazing data.

September 5th, 2020

New paper from the Janzen lab.

August 7th, 2020

"Gemeinsamer Promotionspreis der Unterfränkischen Gedenkjahrstiftung für Wissenschaft und der Universität Würzburg" goes to Sarah Schuster

August 5th, 2020

New preprint on phylogeny: nice collaboration with the bioinformatics department

July 29th, 2020

Irene defended her PhD thesis, on how telomeres connect to the nuclear membrane during meiosis. Well done !

July 20th, 2020

A new Preprint from ZEB.

May 26th, 2020

DFG funds the new priority programme PoP coordinated by Markus Engstler

April 28th, 2020

Detailed analysis of lamin C2 expression in mouse oocytes

April 24th, 2020

There is no way of stopping the wish for proper scientific discussion.

April 20th, 2020

A beautiful collaboration with Alvaro Acosta-Serrano in Liverpool!

April 4th, 2020

Motility Analysis of Trypanosomatids: Here are the methods we have developed

March 10th, 2020

A CRISPR/Cas9 knock out model for SUN3 demonstrated the essential function of SUN3 in sperm head shaping

February 10th, 2020

Familial primary ovarian insufficiency due to a SYCE1 point mutation

February 10th, 2020

Paper by visiting scientist Fernanda Trovero on lncRNAs in spermatogenesis published in RNA Biology

January 31st, 2020

Hello to all our friends in the UK!

January 29th, 2020

The DZVT has been officially launched

January 23th, 2019 -- A 103, 09:15

What can planarians teach us about cell regulation?

December 19th, 2019

The ZEB-Xmas-party takes it's toll

December 16th, 2019

Sarah graduates with distinction (summa cum laude). Well done!

December 12th, 2019 -- A 103

Isabel talks about the sweet and sour tale of social motility (SoMo) and African trypansomes.

December 12th, 2019

Quantitative electron tomography data published in Scientific Reports

December 12th, 2019

Special issue on “Recent advances in meiosis from DNA replication to chromosome segregation” published by Chromosoma

November 28th, 2019 -- A 103

How the flow is regulated in the endoplasmic reticulum

November 26th, 2019

Markus Engstler on the panel of DAAD's Cosimena conference in Cairo

November 14^th, 2019 --- A103, 09:15

Skin pharmacokinetics and anti-parasitic pharmacodynamics: towards the design of new treatments for cutaneous leishmaniasis.

November 8th, 2019

Paula Castaneda honored by the Brazilian Society of Protozoology in Caxambu

October 31st, 2019

A new preprint, in collaboration with Kristina Djinovic-Carugo's group (Max Perutz Labs, Vienna). Structures of MORN repeat proteins from trypanosomes and apicomplexans, and an analysis of lipid binding.

October 29^th, 2019

A collaboration with Markus Sauer’s lab

October 21^st, 2019

Marie-Christin Spindler’s work published in Communications Biology

October 17th, 2019 -- A 103

Philippe comes along and talks about 'How do motors find the way?'. Join us!

October 15th, 2019-- C102.3, 10:15

Bruno Dallagiovanna visits from Brazil and will lecture on 'Long non-coding RNAs in heart development'

August 2nd, 2019

Sarah Schuster's work on the trypanosome passage through the tsetse fly was awarded one of this years Science Awards. Congratulations!

July 30th, 2019

We have a new preprint on the life cycle of trypanosomes.

July 17, 2019-- C102.3, 11:00

Rohit Shrivastava will talk about the role of the translation initiation factor eIF4E3 during the Leishmania life cycle.

July 4th, 2019 -- C102.3, 10:15

Acquired unsaturated fatty acid catabolism: A feature on the trypanosomatid's way to intracellular parasitism.

June 27th, 2019 -- C102.3, 10:15

Exploiting the tsetse biology for trypanosomiasis control

May 22, 2019

The Würzburg DZVT is inaugurated in the presence of Dr Gerd Müller, Federal Minister of Economic Cooperation and Development

May 16th, 2019 -- C102.3, 10:15

The control of Leishmania flagellum beating and swimming - new lessons from high speed fluorescence microscopy

April 4th, 2019

How does the African trypanosome control expression of its Variant Surface
Glycoprotein coat?

March 2019

Nucleoside analogue activators of cyclic AMP-independent protein kinase A of Trypanosoma

March 21st, 2019

Roberta Sciurano’s work published in Chromosoma

March, 21st, 2019 -- A103, 09:15

Brice will tell us what happens "When African trypanosomes make your skin crawl"

March 7th, 2019 -- A103, 09:15

Jack Sunter will give a ZEB lecture on 'Leishmania flagellar pocket architecture is critical for pathogenicity'.

February 21st, 2019 -- A103, 09:15

Trypanosome AMP-dependent protein kinase activation induces developmental transition from proliferative to the quiescent form: Novel players in the pathway.

February, 7th, 2019 -- A103, 09:15

Sascha Knauf (Deutsches Primatenzentrum, Göttingen) will lecture on "Disease Reservoirs in Wildlife: from Eco Health to One Health"

January 23th, 2019 -- A103, 09:15

TrypClub this week will be given by Sara Sajko (Max F. Perutz Laboratories, Vienna), discussing her PhD project work.

January 24th, 2019 -- A103, 09:15

Exploitation of receptor-mediated ligand uptake for the targeted delivery of antibody-drug conjugates into Trypanosoma brucei.

January 10th, 2019 -- A103, 09:15

We welcome Annette MacLeod from Glasgow, who will give the first ZEB-lecture in 2019. Happy New Year!

December 31st, 2018

Collaboration with Owen Davis’ lab on meiotic telomeres published in Nature Communications.

December 31st, 2018

Paper by visiting scientist Roberta Sciurano on meiosis in a 47, XYY man published in Human Reproduction.

December 18th, 2018

We are very happy to be part of a collaboration headed by Nicolai Siegel's lab, which explored the influence of genome organisation and DNA accessibility on antigenic variation in African trypanosomes.

December 13th, 2018 -- A103, 09:15

Investigating and exploiting parasites weaknesses in lipid and associated metabolism

November 12th, 2018

Trypanosomes can start (but not finish!) nuclear export even when transcription and splicing have not been completed. 

November 15th, 2018 -- A103, 09:15

Elucidating specificity mechanisms in ubiquitin signaling

October 31th, 2018

Collaboration with Thomas Bosch’s lab on the nuclear lamina of non-senescent Hydra published in Aging (Albany, NY).

October 23rd, 2018

The complex enzymology of mRNA decapping: Enzymes of four classes cleave pyrophosphate bonds.

October 22th, 2018 -- C102.3, 12:00 noon

Spliced leader level is a signal for life and affects social motility via exosome secretion in trypanosomes

October 18, 2018 -- A103, 09:15 a.m.

Functional dissection of the Leishmania flagellar proteome using CRISPR-Cas9 knockout screens

October 4th, 2018

New hints about how excess of prelamin A induces muscle fiber weakness during physiological and premature aging.

October 4th, 2018 -- A103, 09:15 a.m.

Human African Trypanosomiasis: Evolution and Cell Death in Trypanosoma brucei.

September 26, 2018 -- A101, 01:15 p.m.

PhD defense

Single-molecule fluorescence microscopy in live Trypanosoma brucei and model membranes

September 20th, 2018 -- A102, 10:45 a.m.

Function and composition of Trypanosoma brucei mitochondrial DNA: use it or lose it.

September 1st, 2018

We have published a review/opinion article in 'Trends in Parasitology', in which we consider the recently extended definition of the interstitium as path for the dispersal of extracellular pathogens.

August 29th, 2018

A unique, historic portrait of the founder of Würzburg Zoology has been moved from our department to the Martin von Wagner Museum, where it will be prominently displayed in the entrance hall.

August 27, 2018

Marie-Christin Spindler’s experimental protocols published in Methods in Molecular Biology.

August 23rd, 2018

Markus Engstler, together with DNTDs and DAHW, presents the Würzburg concept for a Neglected Tropical Diseases Center

July 25th, 2018

Comparative proteomics of the two T. brucei PABPs suggests that PABP2 controls bulk mRNA.

July 16, 2018 -- Seminar A102.3, 11:00 a.m.

Nutrient stress during Giardia dudenalis infection: Who cares about arginine?

July 12th, 2018 -- Seminar A102.3, 10:15 a.m.

The lullaby of Sleeping Sickness

July 1, 2018

Markus Engstler delivers evening lecture at the 11th International Workshop on Engineering of Functional Interfaces

June 28, 2018

Katharina Schücker’s experimental protocols published in Methods in Cell Biology

June 28, 2018 -- Seminar A102.3, 10:15 a.m.

Meiotic arrest in infertile men due to genetic disturbances

June 20-22, 2018

Keynote lecture by Ricardo Benavente at the 4th Spanish Meiosis Meeting

June 12-22, 2018

Advanced electron microscopy for cell biology.

Christian Stigloher, together with Gareth Griffiths and Yannick Schwab, has organized this years EM course, which will take place in our Z7 course building.

June 10-15, 2018

Ricardo Benavente lectured at the Gordon Research Conference on Meiosis (New London, New Hampshire)

June 14th, 2018 -- Seminar A102.3, 10:15 a.m.

How to build a flagellum: Lessons from Trypanosomes

May 31th to June 3rd, 2018

Our work featured is as part of the University's Africa initiatives.

May 30th, 2018 -- Seminar A102.3, 10:15 a.m.

How SPOC executes the Nerve Pinch through transcriptional regulation

Mai 2018

Im Mai besuchen uns Nachwuchsforscher aus der Kita an der Löwenbrücke, am 7.Mai die Grossen und am 29. Mai die Kleinen. 

May 5, 2018 -- Seminar C102.3, 10:15 a.m.

Optical Microspectrometry for studying the underlying dynamics of life: from phase transitions to mechano-transduction

April 23, 2018

Weakening of lamin crosslinks by site specific phosphorylation supports meiotic chromosome movements

April 19, 2018 -- Seminar C102.3, 10:15 a.m.

Life cycle differentiation and the cytoskeleton in Trypanosoma brucei

April 10, 2018

Die erste wissenschaftliche Studie zum Beitrag deutscher Institutionen bei der Forschung zu Vernachlässigten Tropenerkrankungen wird im Bundesministerium für Bildung und Forschung (BMBF) in Berlin vorgestellt. Markus Engstler ist einer der Herausgeber der Studie.

March 28, 2018

Boehringer Ingelheim Fonds awarded Marie a travel grant to take part in the Cold Spring Harbor Laboratory course on Quantitative Imaging

March 28, 2018

We warmly welcome Roberta Sciurano (Buenos Aires) and Fernanda Trovero (Montevideo) who will spend six months in the Benavente lab

March 26, 2018 -- C101.2, 10:00 a.m.

Trypanosomes' magic bullet – Understanding the structural basis of SRA-mediated immune escape in T. b. rhodesiense

March 23, 2018

Sarah (arrow) receives DGP-poster prize for her tsetse fly work

March 21-24, 2018

Eleven of us presented at the Parasitology Meeting in Berlin

March 14, 2018

We have launched a comprehensive online resource that features Theodor Boveri's life and work.

February 17, 2018

Tim Krüger's (nature-inspired) vision of a trypanobot on the issue cover of Micromachines

February 16, 2018

Uli Scheer publishes the rediscovery of Boveri's microscope slides in Würzburg.

February 14, 2018

Interested in doing your PhD in our interdisciplinary department? Perfect time to join us!

February 8, 2018

Novel components of the telomeric shelterin complex were identified in Trypanosome brucei.

February 2, 2018

Science or fiction? Can we design trypanosome-inspired micro-robots? Read our new review.

February 1, 2018

Advance notice for M.Sc. students. Our brand-new module will start in April.

January 25, 2018 -- A103, 09:15 a.m.

Size-dependent organelle transport during phagocytosis

January 17, 2018

Our work on VSG structure and dynamics featured by the European Synchrotron Radiation Facility (ESRF)

January 7, 2018

New review in Cellular Microbiology

November 21, 2017

Our friend and coworker Prof Andrew Nok has passed away. With deep sorrow we remember his brilliant intellect, his kindness and wonderful sense of humor. Markus Engstler

November 13, 2017 -- A103, 09:15 a.m.

Electron cryo microscopy as tool in structural biology

November 13, 2017

Find your favorite thesis project! We are continuously updating the selection of topics ...

November 13, 2017

Ricardo Benavente appointed „Investigador Emérito“ by the Clemente-Estable-Institute for Biological Research in Montevideo

November 8, 2017

Sarah's work in eLIFE featured by Cambridge-based BPoD

November 16, 2017 -- A103, 09:15 a.m.

Structural dissections of the flagellar pocket collar in Trypanosoma brucei and a novel oligomeric lysine methyltranferase from Toxoplasma gondii

October 16, 2017

We welcome all new (and old) students to the winter term. Hope you like our lectures, seminars and courses!

October 12, 2017

The school, co-organized by Susanne Kramer, has been honored by the HRK

September 18 to 22, 2017

Markus Engstler lectured at the International School "From single particle motion to collective behaviour".

September 11, 2017

Our work on the structure-function relationship of VSG published in Nature Microbiology

August 15, 2017

Sarah's work published in eLife

July 27, 2017 -- A103, 09:15 a.m.

MPI Biochemie, Martinsried

Dynamic Mapping of Protein Subcellular Localization through Quantitative Proteomics

July 19, 2017 -- A101, 02:30 p.m.

PhD defence

Helena Reis

July 18, 2017

...we have started to launch our new websites ... will take a while ....

July 13, 2017 -- A103, 09:15 a.m.

Paul-Ehrlich-Institut, Langen

“Paraphagy”, a new autophagy mechanism for Leishmania immune evasion?

June 28, 2017 -- A101, 05:15 p.m.

DKFZ Heidelberg

Adaptive fine tuning of genetic information by DNA mutation and RNA editing

June 21, 2017 -- A101, 02:30 p.m.

PhD defence

Henriette Zimmermann