AG Lackus - Molecular Chemical Ecology

In the field of Molecular Chemical Ecology, we study plant chemical compounds, so-called specialized metabolites, which play an important role in plant-environment interactions. The focus of our research group is to understand the biosynthesis and evolution of specialized metabolites in woody plants (poplars and willows (Salicaceae)) and herbaceous perennials (goldenrod (Asteraceae)). Further goals are to investigate the ecological function of specialized metabolites in biotic plant-environment interactions (herbivores, pathogens), to understand structure-function relationships, and to elucidate the molecular mechanisms leading to the chemical diversity of plant specialized metabolites.

How and when are plant specialized metabolites formed? Which enzymes are involved? Can the formation of metabolites be reconstituted in heterologous hosts?

Is the biosynthesis of specialized metabolites conserved within different plant species/families? Is there a convergent evolution of metabolic pathways?

What is the ecological function of specialized metabolites in plant-environment interactions? Do specialized metabolites have more than one function? What are molecular structure-function relationships?