Deutsch
Neurobiology and Genetics

Publications Wegener

  • Neuronal and endocrine mechanisms underlying the circadian gating of eclosion: insights from Drosophila. Wegener, Christian; Amini, Emad; Cavieres-Lepe, Javier; Ewer, John. In Current Opinion in Insect Science, 66, p. 101286. 2024.
  • The neuropeptide pigment-dispersing factor signals independently of Bruchpilot-labelled active zones in daily remodelled terminals of Drosophila clock neurons. Hofbauer, Benedikt; Zandawala, Meet; Reinhard, Nils; Rieger, Dirk; Werner, Christian; Evers, Jan Felix; Wegener, Christian. In European Journal of Neuroscience, n/a(n/a). 2024.
  • Timed receptor tyrosine kinase signaling couples the central and a peripheral circadian clock in Drosophila.. Cavieres-Lepe, Javier; Amini, Emad; Zabel, Maia; Nässel, Dick R.; Stanewsky, Ralf; Wegener, Christian; Ewer, John. In Proceedings of the National Academy of Sciences, 121(11), p. e2308067121. 2024.
  • The circadian clock is required for rhythmic lipid transport in Drosophila in interaction with diet and photic condition. Amatobi, Kelechi M.; Ozbek-Unal, Ayten Gizem; Schäbler, Stefan; Deppisch, Peter; Helfrich-Förster, Charlotte; Mueller, Martin J.; Wegener, Christian; Fekete, Agnes. In Journal of Lipid Research. 2023.
  • Allatostatin A Signalling: Progress and New Challenges From a Paradigmatic Pleiotropic Invertebrate Neuropeptide Family. Wegener, Christian; Chen, Jiangtian. In Front Physiol, 13, p. 920529. 2022.
  • Adaptation of Drosophila melanogaster to Long Photoperiods of High-Latitude Summers Is Facilitated by the ls-Timeless Allele. Deppisch, Peter; Prutscher, Johanna M.; Pegoraro, Mirko; Tauber, Eran; Wegener, Christian; Helfrich-Förster, Charlotte. In Journal of Biological Rhythms. 2022.
  • A neuroendocrine pathway modulating osmotic stress in Drosophila. Zandawala, Meet; Nguyen, Thomas; Balanyà Segura, Marta; Johard, Helena A. D.; Amcoff, Mirjam; Wegener, Christian; Paluzzi, Jean-Paul; Nässel, Dick R. In PLOS Genetics, 17(3), pp. 1–31. 2021.
  • Natural Zeitgebers Under Temperate Conditions Cannot Compensate for the Loss of a Functional Circadian Clock in Timing of a Vital Behavior in Drosophila. Ruf, Franziska; Mitesser, Oliver; Mungwa, Simon Tii; Horn, Melanie; Rieger, Dirk; Hovestadt, Thomas; Wegener, Christian. In Journal of Biological Rhythms. 2021.
  • Transcriptomic, peptidomic, and mass spectrometry imaging analysis of the brain in the ant Cataglyphis nodus. Habenstein, Jens; Schmitt, Franziska; Liessem, Sander; Ly, Alice; Trede, Dennis; Wegener, Christian; Predel, Reinhard; R{"o}ssler, Wolfgang; Neupert, Susanne. In J Neurochem, 158(2), pp. 391–412. 2021.
  • Natural Zeitgebers Under Temperate Conditions Cannot Compensate for the Loss of a Functional Circadian Clock in Timing of a Vital Behavior in Drosophila. Ruf, Franziska; Mitesser, Oliver; Mungwa, Simon Tii; Horn, Melanie; Rieger, Dirk; Hovestadt, Thomas; Wegener, Christian. In J Biol Rhythms, 36(3), pp. 271–285. 2021.
  • Endocrine signals fine-tune daily activity patterns in Drosophila. Pauls, Dennis; Selcho, Mareike; Räderscheidt, Johanna; Amatobi, Kelechi M; Fekete, Agnes; Krischke, Markus; Hermann-Luibl, Christiane; Ozbek-Unal, Ayten Gizem; Ehmann, Nadine; Itskov, Pavel M; Kittel, Robert J; Helfrich-Förster, Charlotte; Kühnlein, Ronald P; Mueller, Martin J; Wegener, Christian. In Curr Biol, 31(18), pp. 4076–4087.e5. 2021.
  • Loss of function in the Drosophila clock gene period results in altered intermediary lipid metabolism and increased susceptibility to starvation. Schäbler, Stefan; Amatobi, Kelechi M.; Horn, Melanie; Rieger, Dirk; Helfrich-Förster, Charlotte; Mueller, Martin J.; Wegener, Christian; Fekete, Agnes. In Cellular and Molecular Life Sciences, 77, pp. 4939–4956. 2020.
  • ER-Ca2+ sensor STIM regulates neuropeptides required for development under nutrient restriction in Drosophila. Megha; Wegener, Christian; Hasan, Gaiti. In PLOS ONE, 14(7), pp. 1–22. 2019.
  • Reward signaling in a recurrent circuit of dopaminergic neurons and peptidergic Kenyon cells. Lyutova, Radostina; Selcho, Mareike; Pfeuffer, Maximilian; Segebarth, Dennis; Habenstein, Jens; Rohwedder, Astrid; Frantzmann, Felix; Wegener, Christian; Thum, Andreas S.; Pauls, Dennis. In Nature Communications, 10(1), p. 3097-. 2019.
  • Drosophila carboxypeptidase D (SILVER) is a key enzyme in neuropeptide processing required to maintain locomotor activity levels and survival rate. Pauls, Dennis; Hamarat, Yasin; Trufasu, Luisa; Schendzielorz, Tim M.; Gramlich, Gertrud; Kahnt, Jörg; Vanselow, Jens T.; Schlosser, Andreas; Wegener, Christian. In European Journal of Neuroscience. 2019.
  • Peptidergic signaling from clock neurons regulates reproductive dormancy in Drosophila melanogaster. Nagy, Dóra; Cusumano, Paola; Andreatta, Gabriele; Anduaga, Ane Martin; Hermann-Luibl, Christiane; Reinhard, Nils; Gesto, Joao; Wegener, Christian; Mazzotta, Gabriella; Rosato, Ezio; Kyriacou, Charalambos P; Helfrich-Förster, Charlotte; Costa, Rodolfo. In PLoS Genet, 15(6), p. e1008158. 2019.
  • Anatomical characterization of PDF-Tri neurons and peptidergic neurons associated with eclosion behavior in Drosophila. Selcho, Mareike; Mühlbauer, Barbara; Hensgen, Ronja; Shiga, Sakiko; Wegener, Christian; Yasuyama, Kouji. In Journal of Comparative Neurology, 526, pp. 1307–1328. 2018.
  • Metabolic Labeling to Quantify Drosophila Neuropeptides and Peptide Hormones. Kunz, Thomas Otto; Chen, Jiangtian; Megha; Wegener, Christian. In Peptidomics: Methods and Strategies, M. Schrader, L. Fricker (eds.), pp. 175–185. 2018.
  • Neuropeptidomics of the Bed Bug Cimex lectularius. Predel, Reinhard; Neupert, Susanne; Derst, Christian; Reinhardt, Klaus; Wegener, Christian. In Journal of Proteome Research, 17(1), pp. 440–454. 2018.
  • Neuropeptides in the desert ant Cataglyphis fortis: Mass spectrometric analysis, localization, and age-related changes. Schmitt, Franziska; Vanselow, Jens T; Schlosser, Andreas; Wegener, Christian; Rössler, Wolfgang. In J Comp Neurol, 525, pp. 901–918. 2017.
  • Central and peripheral clocks are coupled by a neuropeptide pathway in Drosophila. Selcho, Mareike; Millán, Carola; Palacios-Mu{~n}; Munoz, Angelina; Ruf, Franziska; Ubillo, Lilian; Chen, Jiangtian; Bergmann, Gregor; Ito, Chihiro; Silva, Valeria; Wegener, Christian; Ewer, John. In Nature Communications, 8, p. 8:15563. 2017.
  • WEclMon--A simple and robust camera-based system to monitor Drosophila eclosion under optogenetic manipulation and natural conditions. Ruf, Franziska; Fraunholz, Martin; {"O}chsner, Konrad; Kaderschabek, Johann; Wegener, Christian. In PloS one, 12(6), p. e0180238. 2017.
  • Stereotyped responses of Drosophila peptidergic neuronal ensemble depend on downstream neuromodulators. Mena, Wilson; Diegelmann, S{"o}ren; Wegener, Christian; Ewer, John. In eLife, 5, p. e19686. 2016.
  • Unique features of a global human ectoparasite identified through sequencing of the bed bug genome. Benoit, Joshua B; Adelman, Zach N; Reinhardt, Klaus; Dolan, Amanda; Poelchau, Monica; Jennings, Emily C; Szuter, Elise M; Hagan, Richard W; Gujar, Hemant; Shukla, Jayendra Nath; Menegazzi, Pamela; Wegener, Christian; Peschel, Nicolai et al. In Nat Commun, 7:10165. 2016.
  • Allatostatin a signalling in Drosophila regulates feeding and sleep and is modulated by PDF. Chen, Jiangtian; Reiher, Wencke; Hermann-Luibl, Christiane; Sellami, Azza; Cognigni, Paola; Kondo, Shu; Helfrich-Förster, Charlotte; Veenstra, Jan A; Wegener, Christian. In PLOS Genet, 12(9), p. e1006346. 2016.
  • Chemical identity, function and regulation of enteroendocrine peptides in insects. Wegener, Christian; Veenstra, Jan A. In Curr Opin Insect Sci, 11, pp. 8–13. 2015.
  • Potency of transgenic effectors for neurogenetic manipulation in Drosophila larvae. Pauls, Dennis; von Essen, Alina; Lyutova, Radostina; van Giesen, Lena; Rosner, Ronny; Wegener, Christian; Sprecher, Simon G. In Genetics, 199(1), pp. 25–37. 2015.
  • Immunofluorescence and Genetic Fluorescent Labeling Techniques in the Drosophila Nervous System. Selcho, Mareike; Wegener, Christian. In Immunocytochemistry and Related Techniques, pp. 39–62. 2015.
  • Identification and distribution of SIFamide in the nervous system of the desert locust Schistocerca gregaria. Gellerer, Alina; Franke, Aileen; Neupert, Susanne; Predel, Reinhard; Zhou, Xin; Liu, Shanlin; Reiher, Wencke; Wegener, Christian; Homberg, Uwe. In J Comp Neurol, 523(1), pp. 108–125. 2015.
  • Neuropeptidomics of the carpenter ant Camponotus floridanus. Schmitt, Franziska; Vanselow, Jens T; Schlosser, Andreas; Kahnt Jörg; Rössler Wolfgang; Wegener, Christian. In J Proteome Res, 14(3), pp. 1504–1514. 2015.
  • Peptidomics and processing of regulatory peptides in the fruit fly Drosophila. Pauls, Dennis; Chen, Jiangtian; Reiher, Wencke; Vanselow, Jens T; Schlosser, Andreas; Kahnt, Jörg; Wegener, Christian. In EuPA Open Proteomics, 3, pp. 114–127. 2014.
  • Peptide profiling of the retrocerebral complex and identification of an adipokinetic hormone and short neuropeptide F peptides in diapausing and non-diapausing cherry fruit flies Rhagoletis cerasi (Diptera: Tephritidae). Wegener, Christian. In Mitt Dtsch Ges Allg Angew Entomol, 19, pp. 265–268. 2014.
  • Diverse in-and output polarities and high complexity of local synaptic and non-synaptic signaling within a chemically defined class of peptidergic Drosophila neurons. Karsai, Gergely; Poll{’a}k, Edit; Wacker, Matthias; V{"o}mel, Matthias; Selcho, Mareike; Berta, Gergely; Nachman, Ronald J; Isaac, R Elwyn; Moln{’a}r, L{\’a}szl{’o}; Wegener, Christian. In Front Neural Circuits, 7, p. 127. 2013.
  • Identification and structural characterization of interneurons of the Drosophila brain by monoclonal antibodies of the Würzburg Hybridoma Library. Redondo, Beatriz Blanco; Bunz, Melanie; Halder, Partho; Sadanandappa, Madhumala K.; Mühlbauer, Barbara; Erwin, Felix; Hofbauer, Alois; Rodrigues, Veronica; VijayRaghavan, K.; Ramaswami, Mani; Rieger, Dirk; Wegener, Christian; Helfrich-Förster, Charlotte; Buchner, Erich. In PLOS ONE, 8(9), pp. 1–9. 2013.
  • Peptidomics of the agriculturally damaging larval stage of the cabbage root fly Delia radicum (Diptera: Anthomyiidae). Zoephel, Judith; Reiher, Wencke; Rexer, Karl-Heinz; Kahnt, J{"o}rg; Wegener, Christian. In PloS one, 7, p. e41543. 2012.
  • Functional significance of the copper transporter ATP7 in peptidergic neurons and endocrine cells in Drosophila melanogaster. Sellami, Azza; Wegener, Christian; Veenstra, Jan A. In Letters, 586(20), pp. 3633–3638. 2012.
  • Deficiency of prohormone convertase dPC2 (AMONTILLADO) results in impaired production of bioactive neuropeptide hormones in Drosophila. Wegener, Christian; Herbert, Henrik; Kahnt, Jörg; Bender, Michael; Rhea, Jeanne M. In J Neurochem, 118, pp. 581–595. 2011.
  • A comparative review of short and long neuropeptide F signaling in invertebrates: Any similarities to vertebrate neuropeptide Y signaling?. Nässel, Dick R.; Wegener, Christian. In Peptides, 32(6), pp. 1335–1355. 2011.
  • Peptidomics and Peptide Hormone Processing in the Drosophila Midgut. Reiher, Wencke; Shirras, Christine; Kahnt, Jörg; Baumeister, Stefan; Isaac, R. Elwyn; Wegener, Christian. In J Proteome Res, 10(4), pp. 1881–1892. 2011.
  • The proprotein convertase encoded by amontillado (amon) is required in Drosophila corpora cardiaca endocrine cells producing the glucose regulatory hormone AKH. Rhea, Jeanne M; Wegener, Christian; Bender, Michael. In PLoS Genet, 6(5), p. e1000967. 2010.
  • Direct peptide profiling of brain tissue by MALDI-TOF mass spectrometry. Schachtner, J.; Wegener, C.; Neupert, S.; Predel, R. In Methods Mol Biol, 615, pp. 129–135. 2010.
  • Individual carboxypeptidase D domains have both redundant and unique functions in Drosophila development and behavior. Sidyelyeva, Galyna; Wegener, Christian; Schoenfeld, BrianP.; Bell, AaronJ.; Baker, NicholasE.; McBride, SeanM.J.; Fricker, LloydD. In Cell Mol Life Sci, 67, pp. 2991–3004. 2010.
  • Direct MALDI-TOF Mass Spectrometric Peptide Profiling of Neuroendocrine Tissue of Drosophila. Wegener, Christian; Neupert, Susanne; Predel, Reinhard. In Peptidomics: Methods and Protocols, M. Soloviev (ed.), pp. 117–127. 2010.
  • Neuroarchitecture of Aminergic Systems in the Larval Ventral Ganglion of Drosophila melanogaster. Vömel, Matthias; Wegener, Christian. In {PLoS} {ONE}, 3(3), S. Hochman (ed.), p. e1848. 2008.
  • A large population of diverse neurons in the Drosophila central nervous system expresses short neuropeptide F, suggesting multiple distributed peptide functions. Nässel, Dick R; Enell, Lina E; Santos, Jonathan G; Wegener, Christian; Johard, Helena AD. In BMC Neurosci, 9(1), p. 90. 2008.
  • Molecular evolution of neuropeptides in the genus Drosophila. Wegener, Christian; Gorbashov, Anton. In Genome Biol, 9(8), p. R131. 2008.
  • Comparative neuroanatomy and genomics of hugin and pheromone biosynthesis activating neuropeptide (PBAN). Bader, R.; Wegener, C.; Pankratz, M.J. In Fly, 1(4), pp. 228–231. 2007.
  • Direct peptide profiling of lateral cell groups of the antennal lobes {ofManduca} sextareveals specific composition and changes in neuropeptide expression during development. Utz, Sandra; Huetteroth, Wolf; Wegener, Christian; Kahnt, Jörg; Predel, Reinhard; Schachtner, Joachim. In Dev Neurobiol, 67(6), pp. 764–777. 2007.
  • Neurotransmitter-induced changes in the intracellular calcium concentration suggest a differential central modulation of {CCAP} neuron subsets {inDrosophila}. Vömel, Matthias; Wegener, Christian. In Dev Neurobiol, 67(6), pp. 792–808. 2007.
  • A simple purification protocol for the detection of peptide hormones in the hemolymph of individual insects by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Fastner, Sandy; Predel, Reinhard; Kahnt, Jörg; Schachtner, Joachim; Wegener, Christian. In RAPID COMMUN MASS SP, 21(1), pp. 23–28. 2006.
  • Direct mass spectrometric peptide profiling and fragmentation of larval peptide hormone release sites {in Drosophila} melanogaster reveals tagma-specific peptide expression and differential processing. Wegener, Christian; Reinl, Tobias; Jänsch, Lothar; Predel, Reinhard. In J Neurochem, 96(5), pp. 1362–1374. 2006.
  • Peptidomics of CNS-associated neurohemal systems of adult Drosophila melanogaster: A mass spectrometric survey of peptides from individual flies. Predel, R.; Wegener, C.; Russell, W.K.; Tichy, S.E.; Russell, D.H.; Nachman, R.J. In J Comp Neurol, 474(3), pp. 379–392. 2004.
  • Acetylcholine Increases Intracellular Ca2 Via Nicotinic Receptors in Cultured {PDF}-Containing Clock Neurons of Drosophila. Wegener, C. In J Neurophysiol, 91(2), pp. 912–923. 2003.
  • The periviscerokinin (PVK) peptide family in insects: Evidence for the inclusion of CAP2b as a PVK family member. Wegener, C.; Herbert, Z.; Eckert, M.; Predel, R. In Peptides, 23(4), pp. 605–611. 2002.
  • Periviscerokinins in cockroaches: Release, localization, and taxon-specific action on the hyperneural muscle. Wegener, C.; Linde, D.; Eckert, M. In Gen Comp Endocrinol, 121(1), pp. 1–12. 2001.
  • Peptide-induced Ca2+ movements in a tonic insect muscle: effects of proctolin and periviscerokinin-2. Wegener, Christian; N{"a}ssel, Dick R. In J Neurophysiol, 84(6), pp. 3056–3066. 2000.
  • Quantification of periviscerokinin-1 in the nervous system of the American cockroach, Periplaneta americana: An insect neuropeptide with unusual distribution. Wegener, Christian; Predel, Reinhard; Eckert, Manfred. In Arch Insect Biochem Physiol, 40(4), pp. 203–211. 1999.