Deutsch
  • HEK-293T cells infected with Chlamydia trachomatis expressing chlamydial deubiquitinase Cdu1-FLAG
Chair of Microbiology

Publications

  • Schlötzer J, Schmalix A, Hügelschäffer S, Rieger D, Sauer F, Tully MD, Rudel T, Wiesner S, Kisker C. Linkage-specific ubiquitin binding interfaces modulate the activity of the chlamydial deubiquitinase Cdu1 towards poly-ubiquitin substrates. PLoS Pathog. 2024 Oct 21;20(10):e1012630. doi: 10.1371/journal.ppat.
  •  Wolfgang Eisenreich, Julian Leberfing, Thomas Rudel, Jürgen Heesemann, Werner Goebel, Interactions of SARS-CoV-2 with Human Target Cells—A Metabolic View. Int. J. Mol. Sci. 2024, 25(18), 9977; https://doi.org/10.3390/ijms25189977
  • Rühling, M., Kersting, L., Wagner, F., Schumacher, F, Wigger, D., Helmerich, D.A., Pfeuffer, T., Elflein, R., Kappe, C., Sauer, M., Arenz, C., Kleuser, B., Rudel, T., Fraunholz, M., Seibel, J. Trifunctional sphingomyelin derivatives enable nanoscale resolution of sphingomyelin turnover in physiological and infection processes via expansion microscopy. Nat Commun 15, 7456 (2024). https://doi.org/10.1038/s41467-024-51874-w
  • Hovhannisyan P, Stelzner K, Keicher M, Paprotka K, Neyazi M, Pauzuolis M, Ali WM, Rajeeve K, Bartfeld S, Rudel T. Infection of human organoids supports an intestinal niche for Chlamydia trachomatis. PLoS Pathog. 2024 Aug 22;20(8):e1012144. doi: 10.1371/journal.ppat.
  • Iwanowitsch A, Diessner J, Bergmann B, Rudel T. The JMU-SalVac-System: A Novel, Versatile Approach to Oral Live Vaccine Development. Vaccines (Basel). 2024 Jun 20;12(6):687. doi: 10.3390/vaccines12060687.
  • Wolkersdorfer AM, Bergmann B, Adelmann J, Ebbinghaus M, Günther E, Gutmann M, Hahn L, Hurwitz R, Krähmer R, Leenders F, Lühmann T, Schueler J, Schmidt L, Teifel M, Meinel L, Rudel T. PEGylated Recombinant Aplysia punctata Ink Toxin Depletes Arginine and Lysine and Inhibits the Growth of Tumor Xenografts. ACS Biomater Sci Eng. 2024 May 9. doi: 10.1021/acsbiomaterials.4c00473.
     
  • Rüttiger A-S, Ryan D, Spiga L, Lamm-Schmidt V, Prezza G, Reichardt S, Barquist L, Faber F, Zhu W, Westermann AJ
    The RNA-binding protein RbpB is a central regulator of polysaccharide utilization in gut Bacteroides.
    bioRxiv doi: https://doi.org/10.1101/2023.12.22.572801.
     
  • Hamrock FJ, Ryan D, Shaibah A, Ershova AS, Mogre A, Sulimani MM, Reichardt S, Hokamp K, Westermann AJ, Kröger C
    Global analysis of the RNA-RNA interactome in Acinetobacter baumannii AB5075 uncovers a small regulatory RNA repressing the virulence-related outer membrane protein CarO.
    bioRxiv doi: https://doi.org/10.1101/2023.12.04.569942.
     
  • Vollmuth N*, Bridgers BE*, Armstrong ML, Gildea A, Wood J, Espinal ER, Hooven TA, Barbieri G, Westermann AJ, Sauerwein T, Förstner KU, Schubert-Unkmeir A, Kim BJ (2024)
    Group B streptococcal transcriptome when interacting with brain endothelial cells.
    Journal of Bacteriology (in press).
     
  • Prezza G, Liao C, Reichardt S, Beisel CL, Westermann AJ (2024)
    CRISPR-based screening of small RNA modulators of bile susceptibility in Bacteroides thetaiotaomicron.
    PNAS 121(6):e2311323121. DOI: 10.1073/pnas.2311323121
     
  • Prezza G, Westermann AJ
    CRISPR interference-based functional small RNA genomics.
    Methods in Molecular Biology 2024:2741:101-116. DOI: 10.1007/978-1-0716-3565-0_6
     
  •  Ryan D, Bornet E, Prezza G, Varshini Alampalli S, Franco de Carvalho T, Felchle H, Ebbecke T, Hayward R, Deutschbauer AM, Barquist L, Westermann AJ (2024)
    An expanded transcriptome atlas for Bacteroides thetaiotaomicron reveals a small RNA that modulates tetracycline sensitivity.
    Nature Microbiology 9(4):1130-1144. DOI: 10.1038/s41564-024-01642-9
     
  • Jenniches L, Michaux C, Popella L, Reichardt S, Vogel J, Westermann AJ, Barquist L (2024)
    Improved RNA stability estimation through Bayesian modeling reveals most Salmonella transcripts have sub-minute half-lives.
    PNAS 121(14):e2308814121. DOI: 10.1073/pnas.2308814121
     
  • Zhang K, Repnik U, Diab N, Friske D, Pütz A, Hensel M, Förstner KU, Westermann AJ, Dupont A, Hornef MW (2024)
    Non-professional efferocytosis of Salmonella-infected intestinal epithelial cells in the neonate host.
    Journal of Experimental Medicine 221 (3): e20231237. DOI: 10.1084/jem.20231237
     
  • Kumar N, Prakash PG, Wentland C, Kurian SM, Jethva G, Brinkmann V, Mollenkopf HJ, Krammer T, Toussaint C, Saliba AE, Biebl M, Jürgensen C, Wiedenmann B, Meyer TF, Gurumurthy RK, Chumduri C. Decoding spatiotemporal transcriptional dynamics and epithelial fibroblast crosstalk during gastroesophageal junction development through single cell analysis. Nat Commun. 2024 Apr 9;15(1):3064. doi: 10.1038/s41467-024-47173-z.
     
  • Gurumurthy RK, Kumar N, Chumduri C. Culturing and Differentiation of Patient-Derived Ectocervical Epithelial Stem Cells Using Air-Liquid Interphase and Matrigel Scaffold. Methods Mol Biol. 2024;2749:109-121. doi: 10.1007/978-1-0716-3609-1_11.
     
  • Brenzinger S, Airoldi M, Ogunleye AJ, Jugovic K, Amstalden MK, Brochado AR. The Vibrio cholerae CBASS phage defence system modulates resistance and killing by antifolate antibiotics. Nat Microbiol. 2024 Jan;9(1):251-262. doi: 10.1038/s41564-023-01556-y.

  • Dong J, Holthaus D, Peters C, Koster S, Ehsani M, Quevedo-Olmos A, Berger H, Zarobkiewicz M, Mangler M, Gurumurthy RK, Hedemann N, Chumduri C, Kabelitz D, Meyer TF. γδ T cell-mediated cytotoxicity against patient-derived healthy and cancer cervical organoids. Front Immunol. 2023 Nov 27;14:1281646. doi: 10.3389/fimmu.2023.
  • Boll V, Hermanns T, Uthoff M, Erven I, Hörner EM, Kozjak-Pavlovic V, Baumann U, Hofmann K. Functional and structural diversity in deubiquitinases of the Chlamydia-like bacterium Simkania negevensis. Nat Commun. 2023 Nov 13;14(1):7335. doi: 10.1038/s41467-023-43144-y.
  • Bayer J, Becker J, Liu X, Gritsch L, Daiber E, Korn N, Oesterhelt F, Fraunholz M, Weber A, Wolz C. Differential survival of Staphylococcal species in macrophages. Mol Microbiol. 2023 Oct 28. doi: 10.1111/mmi.15184.
  • Vitale I, Pietrocola F, Guilbaud E, ...., Thomas Rudel,...., Lorenzo Galluzzi. Apoptotic cell death in disease-Current understanding of the NCCD 2023. Cell Death Differ. 2023 May;30(5):1097-1154. doi: 10.1038/s41418-023-01153-w.
  • Stelzner K, Vollmuth N, Rudel T. Intracellular lifestyle of Chlamydia trachomatis and host-pathogen interactions. Nat Rev Microbiol. 2023 Feb 14. doi: 10.1038/s41579-023-00860-y.
  • Steiner T, Zachary M, Bauer S, Müller MJ, Krischke M, Radziej S, Klepsch M, Huettel B, Eisenreich W, Rudel T, Beier D. Central Role of Sibling Small RNAs NgncR_162 and NgncR_163 in Main Metabolic Pathways of Neisseria gonorrhoeae. mBio. 2023 Jan 4:e0309322. doi: 10.1128/mbio.03093-22

  • Vollmuth N, Schlicker L, Guo Y, Hovhannisyan P, Janaki-Raman S, Kurmasheva N, Schmitz W, Schulze A, Stelzner K, Rajeeve K, Rudel T. c-Myc plays a key role in IFN-γ-induced persistence of Chlamydia trachomatis. Elife. 2022 Sep 26;11:e76721. doi: 10.7554/eLife.76721.
     
  • Lang JC, Seiß EA, Moldovan A, Müsken M, Sauerwein T, Fraunholz M, Müller AJ, Goldmann O, Medina E. A Photoconvertible Reporter System for Bacterial Metabolic Activity Reveals That Staphylococcus aureus Enters a Dormant-Like State to Persist within Macrophages. mBio. 2022 Sep 14:e0231622. doi: 10.1128/mbio.02316-22.
  • Eisenreich W, Rudel T, Heesemann J, Goebel W. Link Between Antibiotic Persistence and Antibiotic Resistance in Bacterial Pathogens. Front Cell Infect Microbiol. 2022 Jul 19;12:900848. doi: 10.3389/fcimb.2022.900848.
  • Gurumurthy RK, Koster S, Kumar N, Meyer TF, Chumduri C. Patient-derived and mouse endo-ectocervical organoid generation, genetic manipulation and applications to model infection. Nat Protoc. 2022 May 11. doi: 10.1038/s41596-022-00695-6.
  • Hennig T, Prusty AB, Kaufer BB, Whisnant AW, Lodha M, Enders A, Thomas J, Kasimir F, Grothey A, Klein T, Herb S, Jürges C, Sauer M, Fischer U, Rudel T, Meister G, Erhard F, Dölken L, Prusty BK. Selective inhibition of miRNA processing by a herpesvirus-encoded miRNA.Nature. 2022 May 4. doi: 10.1038/s41586-022-04667-4.
  • Herbert SL, Fick A, Heydarian M, Metzger M, Wöckel A, Rudel T, Kozjak-Pavlovic V, Wulff C. Establishment of the SIS scaffold-based 3D model of human peritoneum for studying the dissemination of ovarian cancer.J Tissue Eng. 2022 Mar 23;13:20417314221088514. doi: 10.1177/20417314221088514.
  • Koster S, Gurumurthy RK, Kumar N, Prakash PG, Dhanraj J, Bayer S, Berger H, Kurian SM, Drabkina M, Mollenkopf HJ, Goosmann C, Brinkmann V, Nagel Z, Mangler M, Meyer TF, Chumduri C. Modelling Chlamydia and HPV co-infection in patient-derived ectocervix organoids reveals distinct cellular reprogramming. Nat Commun. 2022 Feb 24;13(1):1030. doi: 10.1038/s41467-022-28569-1.
     
  • Heydarian M, Rühl E, Rawal R, Kozjak-Pavlovic V. Tissue Models for Neisseria gonorrhoeae Research-From 2D to 3D. Front Cell Infect Microbiol. 2022 Feb 11;12:840122. doi: 10.3389/fcimb.2022.840122.
  • Cable J, Rappuoli R, Klemm EJ, Kang G, Mutreja A, Wright GJ, Pizza M, Castro SA, Hoffmann JP, Alter G, Carfi A, Pollard AJ, Krammer F, Gupta RK, Wagner CE, Machado V, Modjarrad K, Corey L, B Gilbert P, Dougan G, Lurie N, Bjorkman PJ, Chiu C, Nemes E, Gordon SB, Steer AC, Rudel T, Blish CA, Sandberg JT, Brennan K, Klugman KP, Stuart LM, Madhi SA, Karp CL. Innovative vaccine approaches-a Keystone Symposia report. Ann N Y Acad Sci. 2022 May;1511(1):59-86. doi: 10.1111/nyas.14739.

  • Peters S, Fohmann I, Rudel T, Schubert-Unkmeir A. A Comprehensive Review on the Interplay between Neisseria spp. and Host Sphingolipid Metabolites. Cells. 2021 Nov 17;10(11):3201. doi: 10.3390/cells10113201.
  • Zachary M, Bauer S, Klepsch M, Wagler K, Hüttel B, Rudel T, Beier D. Identification and initial characterization of a new pair of sibling sRNAs of Neisseria gonorrhoeae involved in type IV pilus biogenesis. Microbiology (Reading). 2021 Sep;167(9). doi: 10.1099/mic.0.001080
  • Stelzner K, Boyny A, Hertlein T, Sroka A, Moldovan A, Paprotka K, Kessie D, Mehling H, Potempa J, Ohlsen K, Fraunholz MJ, Rudel T. Intracellular Staphylococcus aureus employs the cysteine protease staphopain A to induce host cell death in epithelial cells. PLoS Pathog. 2021 Sep 2;17(9):e1009874. doi: 10.1371/journal.ppat.1009874.
     
  • Martina Klünemann, Sergej Andrejev, Sonja Blasche, Andre Mateus, Prasad Phapale, Saravanan Devendran, Johanna Vappiani, Bernd Simon, Timothy A. Scott, Eleni Kafkia, Dimitrios Konstantinidis, Katharina Zirngibl, Eleonora Mastrorilli, Manuel Banzhaf, Marie-Therese Mackmull, Felix Hövelmann, Leo Nesme, Ana Rita Brochado, Lisa Maier, Thomas Bock, Vinita Periwal, Manjeet Kumar, Yongkyu Kim, Melanie Tramontano, Carsten Schultz, Martin Beck, Janosch Hennig, Michael Zimmermann, Daniel C. Sévin, Filipe Cabreiro, Mikhail M. Savitski, Peer Bork, Athanasios Typas & Kiran R. Patil. Bioaccumulation of therapeutic drugs by human gut bacteria. 2021 Sept 8. https://doi.org/10.1038/s41586-021-03891-8
  • Krones D, Rühling M, Becker KA, Kunz TC, Sehl C, Paprotka K, Gulbins E, Fraunholz M. Staphylococcus aureus α-Toxin Induces Acid Sphingomyelinase Release From a Human Endothelial Cell Line. Front Microbiol. 2021 Jul 29;12:694489. doi: 10.3389/fmicb.2021.694489.
  • Kunz TC, Rühling M, Moldovan A, Paprotka K, Kozjak-Pavlovic V, Rudel T, Fraunholz M. The Expandables: Cracking the Staphylococcal Cell Wall for Expansion Microscopy. Front Cell Infect Microbiol. 2021 Mar 16;11:644750. doi: 10.3389/fcimb.2021.644750.
  • Chumduri C, Gurumurthy RK, Berger H, Dietrich O, Kumar N, Koster S, Brinkmann V, Hoffmann K, Drabkina M, Arampatzi P, Son D, Klemm U, Mollenkopf HJ, Herbst H, Mangler M, Vogel J, Saliba AE, Meyer TF. Opposing Wnt signals regulate cervical squamocolumnar homeostasis and emergence of metaplasia. Nat Cell Biol. 2021 Feb;23(2):184-197. doi: 10.1038/s41556-020-00619-0.
     
  • Eisenreich W, Rudel T, Heesemann J, Goebel W. Persistence of Intracellular Bacterial Pathogens-With a Focus on the Metabolic Perspective. Front Cell Infect Microbiol. 2021 Jan 14;10:615450. doi: 10.3389/fcimb.2020.615450.
     
  • Motaharehsadat Heydarian, Matthias Schweinlin, Thomas Schwarz, Ravisha Rawal, Heike Walles, Marco Metzger, Thomas Rudel*, Vera Kozjak-Pavlovic*. Triple co-culture and perfusion bioreactor for studying the interaction between Neisseria gonorrhoeae and neutrophils: A novel 3D tissue model for bacterial infection and immunity. Journal of Tissue Engineering. 2021 Jan 21; https://doi.org/10.1177/2041731420988802
     
  • Kessie DK, Lodes N, Oberwinkler H, Goldman WE, Walles T, Steinke M, Gross R. Activity of Tracheal Cytotoxin of Bordetella pertussis in a Human Tracheobronchial 3D Tissue Model. Front Cell Infect Microbiol. 2021 Jan 19;10:594932. doi: https://doi.org/10.3389/fcimb.2020.614994

  • Stelzner K, Winkler AC, Liang C, Boyny A, Ade CP, Dandekar T, Fraunholz MJ, Rudel T. Intracellular Staphylococcus aureus Perturbs the Host Cell Ca2+ Homeostasis To Promote Cell Death. mBio. 2020 Dec 15;11(6):e02250-20. doi: 10.1128/mBio.02250-20.
  • Götz R, Kunz TC, Fink J, Solger F, Schlegel J, Seibel J, Kozjak-Pavlovic V, Rudel T, Sauer M. Nanoscale imaging of bacterial infections by sphingolipid expansion microscopy. Nat Commun. 2020 Dec 2;11(1):6173. doi: 10.1038/s41467-020-19897-1.
  • Tragust S, Herrmann C, Häfner J, Braasch R, Tilgen C, Hoock M, Milidakis MA, Gross R, Feldhaar H. Formicine ants swallow their highly acidic poison for gut microbial selection and control. Elife. 2020 Nov 3;9:e60287. doi: 10.7554/eLife.60287.
  • Koch RD, Hörner EM, Münch N, Maier E, Kozjak-Pavlovic V. Modulation of Host Cell Death and Lysis Are Required for the Release of Simkania negevensis. Front Cell Infect Microbiol. 2020 Oct 29;10:594932. doi: 10.3389/fcimb.2020.594932.
  • Yang T, Heydarian M, Kozjak-Pavlovic V, Urban M, Harbottle RP, Rudel T. Folliculin Controls the Intracellular Survival and Trans-Epithelial Passage of Neisseria gonorrhoeae. Front Cell Infect Microbiol. 2020 Sep 4;10:422. doi: 10.3389/fcimb.2020.00422.
     
  • Groma M, Horst SA, Das S, Huettel B, Klepsch M, Rudel T, Medina E, Fraunholz M. 2020. Identification of a Novel LysR-Type Transcriptional Regulator in Staphylococcus aureus That Is Crucial for Secondary Tissue Colonization during Metastatic Bloodstream Infection. mBio 11:e01646-20.
    DOI: 10.1128/mBio.01646-20
     
  • Rajeeve K, Vollmuth N, Janaki-Raman S, Wulff TF, Baluapuri A, Dejure FR, Huber C, Fink J, Schmalhofer M, Schmitz W, Sivadasan R, Wolf E, Eisenreich W, Schulze A, Seibel J, Rudel T. Reprogramming of host glutamine metabolism during Chlamydia trachomatis infection and its key role in peptidoglycan synthesis. Nat Microbiol. 2020 Aug 3. doi: 10.1038/s41564-020-0762-5.
     
  • Kunz TC, Götz R, Gao S, Sauer M, Kozjak-Pavlovic V. Using Expansion Microscopy to Visualize and Characterize the Morphology of Mitochondrial Cristae. Front Cell Dev Biol. 2020 Jul 15;8:617. doi: 10.3389/fcell.2020.0061
  • Solger F, Kunz TC, Fink J, Paprotka K, Pfister P, Hagen F, Schumacher F, Kleuser B, Seibel J, Rudel T. A Role of Sphingosine in the Intracellular Survival of Neisseria gonorrhoeae. Front Cell Infect Microbiol. 2020 May 12;10:215. doi: 10.3389/fcimb.2020.00215.
     
  • Domenech A, Brochado AR, Sender V, Hentrich K, Henriques-Normark B, Typas A, Veening JW. Proton Motive Force Disruptors Block Bacterial Competence and Horizontal Gene Transfer. Cell Host Microbe. 2020 Feb 22. pii: S1931-3128(20)30073-1. doi: 10.1016/j.chom.2020.02.002.

  • Gulve N, Rudel T. Chlamydia trachomatis and human herpesvirus 6 infections in ovarian cancer-Casual or causal? PLoS Pathog. 2019 Nov 7;15(11):e1008055. doi: 10.1371/journal.ppat.1008055.
     
  • Yang M, Rajeeve K, Rudel T, Dandekar T. Comprehensive Flux Modeling of Chlamydia trachomatis Proteome and qRT-PCR Data Indicate Biphasic Metabolic Differences Between Elementary Bodies and Reticulate Bodies During Infection. Front Microbiol. 2019 Oct 15;10:2350. doi: 10.3389/fmicb.2019.02350.
     
  • Auer D, Hügelschäffer SD, Fischer AB, Rudel T. The chlamydial deubiquitinase Cdu1 supports recruitment of Golgi vesicles to the inclusion. Cell Microbiol. 2019 Nov 1:e13136. doi: 10.1111/cmi.13136.
     
  • Wagner F, Kunz TC, Chowdhury SR, Thiede B, Fraunholz M, Eger D, Kozjak-Pavlovic V. Armadillo repeat-containing protein 1 is a dual localization protein associated with mitochondrial intermembrane space bridging complex. PLoS One. 2019 Oct 23;14(10):e0218303. doi: 10.1371/journal.pone.0218303.
     
  • Kunz TC, Kozjak-Pavlovic V. Diverse Facets of Sphingolipid Involvement in Bacterial Infections. Front Cell Dev Biol. 2019 Sep 19;7:203. doi: 10.3389/fcell.2019.00203.
     
  • Kunz TC, Götz R, Sauer M, Rudel T. Detection of Chlamydia Developmental Forms and Secreted Effectors by Expansion Microscopy. Front Cell Infect Microbiol. 2019 Aug 9;9:276. doi: 10.3389/fcimb.2019.00276.
  • Heydarian M, Yang T, Schweinlin M, Steinke M, Walles H, Rudel T, Kozjak-Pavlovic V. Biomimetic Human Tissue Model for Long-Term Study of Neisseria gonorrhoeae Infection. Front Microbiol. 2019 Jul 31;10:1740. doi: m10.3389/ficb.2019.01740
  • Moldovan A, Fraunholz MJ. In or out: Phagosomal escape of Staphylococcus aureus. Cell Microbiol. 2019 Mar;21(3):e12997. doi: 10.1111/cmi.12997.
  • Eisenreich W, Rudel T, Heesemann J, Goebel W. How Viral and Intracellular Bacterial Pathogens Reprogram the Metabolism of Host Cells to Allow Their Intracellular Replication. Front Cell Infect Microbiol. 2019 Mar 4;9:42. doi: 10.3389/fcimb.2019.00042.
  • Gulve N, Prusty BK, Rudel T. Chlamydia trachomatis impairs host base excision repair by downregulating polymerase β. Cell Microbiol. 2019 Apr;21(4):e12986. doi: 10.1111/cmi.12986.

  • Prusty BK, Gulve N, Chowdhury SR, Schuster M, Strempel S, Descamps V, Rudel T. HHV-6 encoded small non-coding RNAs define an intermediate and early stage in viral reactivation. NPJ Genom Med. 2018 Sep 5;3:25. doi: 10.1038/s41525-018-0064-5.
     
  • Horn J, Klepsch M, Manger M, Wolz C, Rudel T, Fraunholz M.  The long non-coding RNA SSR42 controls Staphylococcus aureus α-toxin transcription in response to environmental stimuli. J Bacteriol. 2018 Aug 27. pii: JB.00252-18. doi: 10.1128/JB.00252-18.
  • Fischer A, Rudel T. Safe haven under constant attack-The Chlamydia-containing vacuole. Cell Microbiol. 2018 Oct;20(10):e12940. doi: 10.1111/cmi.12940.
  • Prusty BK, Gulve N, Chowdhury SR, Schuster M, Strempel S, Descamps V, Rudel T.  HHV-6 encoded small non-coding RNAs define an intermediate and early stage in viral reactivation. NPJ Genom Med. 2018 Sep 5;3:25. doi: 10.1038/s41525-018-0064-5.
  • Horn J, Klepsch M, Manger M, Wolz C, Rudel T, Fraunholz M. The long non-coding RNA SSR42 controls Staphylococcus aureus α-toxin transcription in response to environmental stimuli. J Bacteriol. 2018 Aug 27. pii: JB.00252-18. doi: 10.1128/JB.00252-18.
  • Horn J, Stelzner K, Rudel T, Fraunholz M. Inside job: Staphylococcus aureus host-pathogen interactions. Int J Med Microbiol. 2018 Aug;308(6):607-624. doi: 10.1016/j.ijmm.2017.11.009.
  • Rajeeve K, Das S, Prusty BK, Rudel T.  Chlamydia trachomatis paralyses neutrophils to evade the host innate immune response. Nat Microbiol. 2018 Jul;3(7):824-835. doi: 10.1038/s41564-018-0182-y.
  • Prusty BK, Chowdhury SR, Gulve N, Rudel T.  Peptidase Inhibitor 15 (PI15) Regulates Chlamydial CPAF Activity. Front Cell Infect Microbiol. 2018 May 30;8:183. doi: 10.3389/fcimb.2018.00183.
  • Nadella V, Mohanty A, Sharma L, Yellaboina S, Mollenkopf HJ, Mazumdar VB, Palaparthi R, Mylavarapu MB, Maurya R, Kurukuti S, Rudel T, Prakash H.  Inhibitors of Apoptosis Protein Antagonists (Smac Mimetic Compounds) Control Polarization of Macrophages during Microbial Challenge and Sterile Inflammatory Responses. Front Immunol. 2018 Jan 9;8:1792. doi: 10.3389/fimmu.2017.01792.

  • Thakur C, Rapp UR, Rudel T. Cysts mark the early stage of metastatic tumor development in non-small cell lung cancer. Oncotarget. 2017 Dec 30;9(5):6518-6535. doi: 10.18632/oncotarget.23785.
  • Wu Y, Pons V, Goudet A, Panigai L, Fischer A, Herweg JA, Kali S, Davey RA, Laporte J, Bouclier C, Yousfi R, Aubenque C, Merer G, Gobbo E, Lopez R, Gillet C, Cojean S, Popoff MR, Clayette P, Le Grand R, Boulogne C, Tordo N, Lemichez E, Loiseau PM, Rudel T, Sauvaire D, Cintrat JC, Gillet D, Barbier J.  ABMA, a small molecule that inhibits intracellular toxins and pathogens by interfering with late endosomal compartments. Sci Rep. 2017 Nov 14;7(1):15567. doi: 10.1038/s41598-017-15466-7.
  • Haas A, Hensel M, Lührmann A, Rudel T, Saftig P, Schaible UE. Intracellular compartments of pathogens: Highways to hell or stairways to heaven? Int J Med Microbiol. 2017 Oct 26. pii: S1438-4221(17)30536-2. doi: 10.1016/j.ijmm.2017.10.009.
  • Kozjak-Pavlovic V, Herweg JA, Rudel T.  The role of host cell organelles in the development of Simkania negevensis. Int J Med Microbiol. 2017 Oct 28. pii: S1438-4221(17)30336-3. doi: 10.1016/j.ijmm.2017.10.008.
  • Bauer S, Helmreich J, Zachary M, Kaethner M, Heinrichs E, Rudel T, Beier D. The sibling sRNAs NgncR_162 and NgncR_163 of Neisseria gonorrhoeae participate in the expression control of metabolic, transport and regulatory proteins. Microbiology. 2017 Nov;163(11):1720-1734. doi: 10.1099/mic.0.000548.
  • Eisenreich W, Rudel T, Heesemann J, Goebel W. To Eat and to Be Eaten: Mutual Metabolic Adaptations of Immune Cells and Intracellular Bacterial Pathogens upon Infection. Front Cell Infect Microbiol. 2017 Jul 13;7:316. doi: 10.3389/fcimb.2017.00316.
  • Chowdhury SR, Rudel T.  Chlamydia and mitochondria - an unfragmented relationship. Microb Cell. 2017 Jun 14;4(7):233-235. doi: 10.15698/mic2017.07.582.
  • Tanwer P, Bauer S, Heinrichs E, Panda G, Saluja D, Rudel T, Beier D.  Post-transcriptional regulation of target genes by the sRNA FnrS in Neisseria gonorrhoeae. Microbiology. 2017 Jul;163(7):1081-1092. doi: 10.1099/mic.0.000484.
  • Fischer A, Harrison KS, Ramirez Y, Auer D, Chowdhury SR, Prusty BK, Sauer F, Dimond Z, Kisker C, Scott Hefty P, Rudel T.Chlamydia trachomatis-containing vacuole serves as deubiquitination platform to stabilize Mcl-1 and to interfere with host defense. Elife. 2017 Mar 28 e21465. doi: 10.7554/eLife.21465. PMID: 28347402
  • Gupta N, Noel R, Goudet A, Hinsinger K, Michau A, Pons V, Abdelkafi H, Secher T, Shima A, Shtanko O, Sakurai Y, Cojean S, Pomel S, Lievin-Le Moal V, Leignel V, Herweg JA, Fischer A, Johannes L, Harrison K, Beard PM, Clayette P, Le Grand R, Rayner JO, Rudel T, Vacus J, Loiseau PM, Davey RA, Oswald E, Cintrat JC, Barbier J, Gillet D. Inhibitors of retrograde trafficking active against ricin and Shiga toxins also protect cells from several viruses, Leishmania and Chlamydiales. Chem Biol Interact. 2017 Apr 1;267:96-103 doi: 10.1016/j.cbi.2016.10.005 PMID: 27712998
     
  • Chowdhury SR, Reimer A, Sharan M, Kozjak-Pavlovic V, Eulalio A, Prusty BK, Fraunholz M, Karunakaran K, Rudel T. Chlamydia preserves the mitochondrial network necessary for replication via microRNA-dependent inhibition of fission. J Cell Biol. 2017 Mar 22. pii: jcb.201608063. doi: 10.1083/jcb.201608063 PMID: 28330939
     
  • Mehlitz A, Eylert E, Huber C, Lindner B, Vollmuth N, Karunakaran K, Goebel W, Eisenreich W, Rudel T. Metabolic adaptation of Chlamydia trachomatis to mammalian host cells. Mol Microbiol. 2017 Mar 103(6):1004-1019. doi: 10.1111/mmi.13603 PMID: 27997721
     
  • Prusty BK, Gulve N, Rasa S, Murovska M, Hernandez PC, Ablashi DV. Possible chromosomal and germline integration of human herpesvirus 7. J Gen Virol. 2017 Feb 98(2):266-274. doi: 10.1099/jgv.0.000692 PMID: 28284243

  • Richter E, Harms M, Ventz K, Nölker R, Fraunholz MJ, Mostertz J, Hochgräfe F. Quantitative Proteomics Reveals the Dynamics of Protein Phosphorylation in Human Bronchial Epithelial Cells during Internalization, Phagosomal Escape, and Intracellular Replication of Staphylococcus aureus. J Proteome Res. 2016 Dec 2;15(12):4369-4386 PMID: 27762562
     
  • Das BB, Rakheja D, Lacelle C, Sedlak RH, Gulve N, Chowdhury SR, Prusty BK. Possible progesterone-induced gestational activation of chromosomally integrated human herpesvirus 6B and transplacental transmission of activated human herpesvirus 6B. J Heart Lung Transplant. 2016 Nov 35(11):1373-1376. doi: 10.1016/j.healun.2016.08.009 PMID: 27646062
  • Gupta SK, Gross R, Dandekar T. An antibiotic target ranking and prioritization pipeline combining sequence, structure and network-based approaches exemplified for Serratia marcescens. Gene. 2016 Oct 10;591(1):268-78. doi: 10.1016/j.gene.2016.07.030 PMID: 27425866
  • Reimer A, Seufert F, Weiwad M, Ebert J, Bzdyl NM, Kahler CM, Sarkar-Tyson M, Holzgrabe U, Rudel T, Kozjak-Pavlovic V. Inhibitors of macrophage infectivity potentiator-like PPIases affect neisserial and chlamydial pathogenicity. Int J Antimicrob Agents. 2016 Oct 48(4):401-8. doi: 10.1016/j.ijantimicag.2016.06.020 PMID: 27516227
     
  • Blättner S, Das S, Paprotka K, Eilers U, Krischke M, Kretschmer D, Remmele CW, Dittrich M, Müller T, Schuelein-Voelk C, Hertlein T, Mueller MJ, Huettel B, Reinhardt R, Ohlsen K, Rudel T, Fraunholz MJ. Staphylococcus aureus Exploits a Non-ribosomal Cyclic Dipeptide to Modulate Survival within Epithelial Cells and Phagocytes. PLoS Pathog. 2016 Sep 15;12(9):e1005857 doi: 10.1371/journal.ppat.1005857 PMID: 27632173; PMCID: PMC5025175
     
  • Kupper M, Stigloher C, Feldhaar H, Gross R. Distribution of the obligate endosymbiont Blochmannia floridanus and expression analysis of putative immune genes in ovaries of the carpenter ant Camponotus floridanus. Arthropod Struct Dev. 2016 Sep 45(5):475-487. doi: 10.1016/j.asd.2016.09.004 PMID: 27664781
     
  • Strobel M, Pförtner H, Tuchscherr L, Völker U, Schmidt F, Kramko N, Schnittler HJ, Fraunholz MJ, Löffler B, Peters G, Niemann S. Post-invasion events after infection with Staphylococcus aureus are strongly dependent on both the host cell type and the infecting S. aureus strain. Clin Microbiol Infect. 2016 Sep 22(9):799-809. doi: 10.1016/j.cmi.2016.06.020 PMID: 27393124
     
  • Münzenmayer L, Geiger T, Daiber E, Schulte B, Autenrieth SE, Fraunholz M, Wolz C. Influence of Sae-regulated and Agr-regulated factors on the escape of Staphylococcus aureus from human macrophages. Cell Microbiol. 2016 Aug 18(8):1172-83. doi: 10.1111/cmi.12577 PMID: 26895738
     
  • Gulve N, Kimmerling K, Johnston AD, Krueger GR, Ablashi DV, Prusty BK. Anti-herpesviral effects of a novel broad range anti-microbial quaternary ammonium silane, K21. Antiviral Res. 2016 Jul 131:166-73. doi: 10.1016/j.antiviral.2016.05.004 PMID: 27181377
     
  • Das S, Lindemann C, Young BC, Muller J, Österreich B, Ternette N, Winkler AC, Paprotka K, Reinhardt R, Förstner KU, Allen E, Flaxman A, Yamaguchi Y, Rollier CS, van Diemen P, Blättner S, Remmele CW, Selle M, Dittrich M, Müller T, Vogel J, Ohlsen K, Crook DW, Massey R, Wilson DJ, Rudel T, Wyllie DH, Fraunholz MJ. Natural mutations in a Staphylococcus aureus virulence regulator attenuate cytotoxicity but permit bacteremia and abscess formation. Proc Natl Acad Sci U S A. 2016 May 31;113(22):E3101-10 doi: 10.1073/pnas.1520255113 PMID: 27185949; PMCID: PMC4896717
     
  • Fischer A, Rudel T. Subversion of Cell-Autonomous Host Defense by Chlamydia Infection. Curr Top Microbiol Immunol. 2016 May 13. PMID: 27169422
     
  • Das BB, Prusty BK. Clinical Relevance of Detection of HHV-6 by PCR DNA Test in the Blood for Diagnosing Myocarditis. Pediatr Cardiol. 2016 Feb 37(2):429-30. doi: 10.1007/s00246-015-1338-7 PMID: 26739004
     
  • Herweg JA, Rudel T. Interaction of Chlamydiae with human macrophages. FEBS J. 2016 Feb 283(4):608-18. doi: 10.1111/febs.13609 PMID: 26613554
     
  • Herweg JA, Pons V, Becher D, Hecker M, Krohne G, Barbier J, Berger H, Rudel T, Mehlitz A. Proteomic analysis of the Simkania-containing vacuole: the central role of retrograde transport. Mol Microbiol. 2016 Jan 99(1):151-71. doi: 10.1111/mmi.13222 PMID: 26374382
     
  • Stefanski HE, Thibert KA, Pritchett J, Prusty BK, Wagner JE, Lund TC. Fatal Myocarditis Associated With HHV-6 Following Immunosuppression in Two Children. Pediatrics. 2016 Jan 137(1). doi: 10.1542/peds.2015-1352 PMID: 26681781

  • Siegl C, Rudel T. Modulation of p53 during bacterial infections. Nat Rev Microbiol. 2015 Dec 13(12):741-8. doi: 10.1038/nrmicro3537 PMID: 26548915
     
  • Gabed N, Yang M, Bey Baba Hamed M, Drici H, Gross R, Dandekar T, Liang C. Draft Genome Sequence of the Moderately Heat-Tolerant Lactococcus lactis subsp. lactis bv. diacetylactis Strain GL2 from Algerian Dromedary Milk. Genome Announc. 2015 Nov 19;3(6). pii: e01334-15 doi: 10.1128/genomeA.01334-15 PMID: 26586883; PMCID: PMC4653785
     
  • Reimer A, Blohm A, Quack T, Grevelding CG, Kozjak-Pavlovic V, Rudel T, Hentschel U, Abdelmohsen UR. Inhibitory activities of the marine streptomycete-derived compound SF2446A2 against Chlamydia trachomatis and Schistosoma mansoni. J Antibiot (Tokyo). 2015 Nov 68(11):674-9. doi: 10.1038/ja.2015.54 PMID: 25990954
     
  • Karunakaran K, Subbarayal P, Vollmuth N, Rudel T. Chlamydia-infected cells shed Gp96 to prevent chlamydial re-infection. Mol Microbiol. 2015 Nov 98(4):694-711. doi: 10.1111/mmi.13151 PMID: 26235316
     
  • Gao S, Nagpal J, Schneider MW, Kozjak-Pavlovic V, Nagel G, Gottschalk A. Optogenetic manipulation of cGMP in cells and animals by the tightly light-regulated guanylyl-cyclase opsin CyclOp. Nat Commun. 2015 Sep 8;6:8046 doi: 10.1038/ncomms9046 PMID: 26345128; PMCID: PMC4569695
     
  • Mechler L, Herbig A, Paprotka K, Fraunholz M, Nieselt K, Bertram R. A novel point mutation promotes growth phase-dependent daptomycin tolerance in Staphylococcus aureus. Antimicrob Agents Chemother. 2015 Sep 59(9):5366-76. doi: 10.1128/AAC.00643-15 PMID: 26100694; PMCID: PMC4538524
     
  • Gupta SK, Kupper M, Ratzka C, Feldhaar H, Vilcinskas A, Gross R, Dandekar T, Förster F. Scrutinizing the immune defence inventory of Camponotus floridanus applying total transcriptome sequencing. BMC Genomics. 2015 Jul 22;16:540 doi: 10.1186/s12864-015-1748-1 PMID: 26198742; PMCID: PMC4508827
     
  • Herweg JA, Hansmeier N, Otto A, Geffken AC, Subbarayal P, Prusty BK, Becher D, Hensel M, Schaible UE, Rudel T, Hilbi H. Purification and proteomics of pathogen-modified vacuoles and membranes. Front Cell Infect Microbiol. 2015 Jun 2;5:48 doi: 10.3389/fcimb.2015.00048 PMID: 26082896; PMCID: PMC4451638
     
  • Eisenreich W, Heesemann J, Rudel T, Goebel W. Metabolic Adaptations of Intracellullar Bacterial Pathogens and their Mammalian Host Cells during Infection (Pathometabolism). Microbiol Spectr. 2015 Jun 3(3). doi: 10.1128/microbiolspec.MBP-0002-2014 PMID: 26185075
     
  • Frank DO, Dengjel J, Wilfling F, Kozjak-Pavlovic V, Häcker G, Weber A. The pro-apoptotic BH3-only protein Bim interacts with components of the translocase of the outer mitochondrial membrane (TOM). PLoS One. 2015 Apr 15;10(4):e0123341. doi: 10.1371/journal.pone.0123341 PMID: 25875815; PMCID: PMC4398440
     
  • Subbarayal P, Karunakaran K, Winkler AC, Rother M, Gonzalez E, Meyer TF, Rudel T. EphrinA2 receptor (EphA2) is an invasion and intracellular signaling receptor for Chlamydia trachomatis. PLoS Pathog. 2015 Apr 23;11(4):e1004846 doi: 10.1371/journal.ppat.1004846 PMID: 25906164; PMCID: PMC4408118
     
  • Tuchscherr L, Bischoff M, Lattar SM, Noto Llana M, Pförtner H, Niemann S, Geraci J, Van de Vyver H, Fraunholz MJ, Cheung AL, Herrmann M, Völker U, Sordelli DO, Peters G, Löffler B. Sigma Factor SigB Is Crucial to Mediate Staphylococcus aureus Adaptation during Chronic Infections. PLoS Pathog. 2015 Apr 29;11(4):e1004870 doi: 10.1371/journal.ppat.1004870 PMID: 25923704; PMCID: PMC4414502
     
  • Ott C, Dorsch E, Fraunholz M, Straub S, Kozjak-Pavlovic V. Detailed analysis of the human mitochondrial contact site complex indicate a hierarchy of subunits. PLoS One. 2015 Mar 17;10(3):e0120213 doi: 10.1371/journal.pone.0120213 PMID: 25781180; PMCID: PMC4363703
     
  • Abdelmohsen UR, Cheng C, Reimer A, Kozjak-Pavlovic V, Ibrahim AK, Rudel T, Hentschel U, Edrada-Ebel R, Ahmed SA. Antichlamydial sterol from the Red Sea sponge Callyspongia aff. implexa. Planta Med. 2015 Mar 81(5):382-7. doi: 10.1055/s-0035-1545721 PMID: 25782033
     
  • Faulstich M, Hagen F, Avota E, Kozjak-Pavlovic V, Winkler AC, Xian Y, Schneider-Schaulies S, Rudel T. Neutral sphingomyelinase 2 is a key factor for PorB-dependent invasion of Neisseria gonorrhoeae. Cell Microbiol. 2015 Feb 17(2):241-53. doi: 10.1111/cmi.12361 PMID: 25224994
     
  • Galluzzi L, Bravo-San Pedro JM, Vitale I, Aaronson SA, Abrams JM, Adam D, Alnemri ES, Altucci L, Andrews D, Annicchiarico-Petruzzelli M, Baehrecke EH, Bazan NG, Bertrand MJ, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Bredesen DE, Brenner C, Campanella M, Candi E, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, Di Daniele N, Dixit VM, Dynlacht BD, El-Deiry WS, Fimia GM, Flavell RA, Fulda S, Garrido C, Gougeon ML, Green DR, Gronemeyer H, Hajnoczky G, Hardwick JM, Hengartner MO, Ichijo H, Joseph B, Jost PJ, Kaufmann T, Kepp O, Klionsky DJ, Knight RA, Kumar S, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lugli E, Madeo F, Malorni W, Marine JC, Martin SJ, Martinou JC, Medema JP, Meier P, Melino S, Mizushima N, Moll U, Muñoz-Pinedo C, Nuñez G, Oberst A, Panaretakis T, Penninger JM, Peter ME, Piacentini M, Pinton P, Prehn JH, Puthalakath H, Rabinovich GA, Ravichandran KS, Rizzuto R, Rodrigues CM, Rubinsztein DC, Rudel T, Shi Y, Simon HU, Stockwell BR, Szabadkai G, Tait SW, Tang HL, Tavernarakis N, Tsujimoto Y, Vanden Berghe T, Vandenabeele P, Villunger A, Wagner EF, Walczak H, White E, Wood WG, Yuan J, Zakeri Z, Zhivotovsky B, Melino G, Kroemer G. Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell Death Differ. 2015 Jan 22(1):58-73. doi: 10.1038/cdd.2014.137 PMID: 25236395; PMCID: PMC4262782
     
  • Bibova I, Hot D, Keidel K, Amman F, Slupek S, Cerny O, Gross R, Vecerek B. Transcriptional profiling of Bordetella pertussis reveals requirement of RNA chaperone Hfq for Type III secretion system functionality. RNA Biol. 2015;12(2):175-85 doi: 10.1080/15476286.2015.1017237 PMID: 25674816; PMCID: PMC4615762

  • Prusty BK, Siegl C, Gulve N, Mori Y, Rudel T. GP96 interacts with HHV-6 during viral entry and directs it for cellular degradation. PLoS One. 2014 Dec 3;9(12):e113962 doi: 10.1371/journal.pone.0113962 PMID: 25470779; PMCID: PMC4254946
     
  • Siegl C, Prusty BK, Karunakaran K, Wischhusen J, Rudel T. Tumor suppressor p53 alters host cell metabolism to limit Chlamydia trachomatis infection. Cell Rep. 2014 Nov 6;9(3):918-29 doi: 10.1016/j.celrep.2014.10.004 PMID: 25437549
     
  • Volceanov L, Herbst K, Biniossek M, Schilling O, Haller D, Nölke T, Subbarayal P, Rudel T, Zieger B, Häcker G. Septins arrange F-actin-containing fibers on the Chlamydia trachomatis inclusion and are required for normal release of the inclusion by extrusion. MBio. 2014 Oct 7;5(5):e01802-14 doi: 10.1128/mBio.01802-14 PMID: 25293760; PMCID: PMC4196233
     
  • Gurumurthy RK, Chumduri C, Karlas A, Kimmig S, Gonzalez E, Machuy N, Rudel T, Meyer TF. Dynamin-mediated lipid acquisition is essential for Chlamydia trachomatis development. Mol Microbiol. 2014 Oct 94(1):186-201. doi: 10.1111/mmi.12751 PMID: 25116793
     
  • Ioakeimidis F, Ott C, Kozjak-Pavlovic V, Violitzi F, Rinotas V, Makrinou E, Eliopoulos E, Fasseas C, Kollias G, Douni E. A splicing mutation in the novel mitochondrial protein DNAJC11 causes motor neuron pathology associated with cristae disorganization, and lymphoid abnormalities in mice. PLoS One. 2014 Aug 11;9(8):e104237 doi: 10.1371/journal.pone.0104237 PMID: 25111180; PMCID: PMC4128653
     
  • Steinke M, Gross R, Walles H, Gangnus R, Schütze K, Walles T. An engineered 3D human airway mucosa model based on an SIS scaffold. Biomaterials. 2014 Aug 35(26):7355-62. doi: 10.1016/j.biomaterials.2014.05.031 PMID: 24912816
     
  • Mehlitz A, Karunakaran K, Herweg JA, Krohne G, van de Linde S, Rieck E, Sauer M, Rudel T. The chlamydial organism Simkania negevensis forms ER vacuole contact sites and inhibits ER-stress. Cell Microbiol. 2014 Aug 16(8):1224-43. doi: 10.1111/cmi.12278 PMID: 24528559
     
  • Albrecht R, Schütz M, Oberhettinger P, Faulstich M, Bermejo I, Rudel T, Diederichs K, Zeth K. Structure of BamA, an essential factor in outer membrane protein biogenesis. Acta Crystallogr D Biol Crystallogr. 2014 Jun 70(Pt 6):1779-89. doi: 10.1107/S1399004714007482 PMID: 24914988
     
  • Baur S, Rautenberg M, Faulstich M, Grau T, Severin Y, Unger C, Hoffmann WH, Rudel T, Autenrieth IB, Weidenmaier C. A nasal epithelial receptor for Staphylococcus aureus WTA governs adhesion to epithelial cells and modulates nasal colonization. PLoS Pathog. 2014 May 1;10(5):e1004089 doi: 10.1371/journal.ppat.1004089
     
  • Grosz M, Kolter J, Paprotka K, Winkler AC, Schäfer D, Chatterjee SS, Geiger T, Wolz C, Ohlsen K, Otto M, Rudel T, Sinha B, Fraunholz M. Cytoplasmic replication of Staphylococcus aureus upon phagosomal escape triggered by phenol-soluble modulin α. Cell Microbiol. 2014 Apr 16(4):451-65. doi: 10.1111/cmi.12233 PMID: 24164701; PMCID: PMC3969633
     
  • Kupper M, Gupta SK, Feldhaar H, Gross R. Versatile roles of the chaperonin GroEL in microorganism-insect interactions. FEMS Microbiol Lett. 2014 Apr 353(1):1-10. doi: 10.1111/1574-6968.12390 PMID: 24460534
     
  • Pfanner N, van der Laan M, Amati P, Capaldi RA, Caudy AA, Chacinska A, Darshi M, Deckers M, Hoppins S, Icho T, Jakobs S, Ji J, Kozjak-Pavlovic V, Meisinger C, Odgren PR, Park SK, Rehling P, Reichert AS, Sheikh MS, Taylor SS, Tsuchida N, van der Bliek AM, van der Klei IJ, Weissman JS, Westermann B, Zha J, Neupert W, Nunnari J. Uniform nomenclature for the mitochondrial contact site and cristae organizing system. J Cell Biol. 2014 Mar 31;204(7):1083-6 doi: 10.1083/jcb.201401006 PMID: 24687277; PMCID: PMC3971754
     
  • Kozjak-Pavlovic V, Prell F, Thiede B, Götz M, Wosiek D, Ott C, Rudel T. C1orf163/RESA1 is a novel mitochondrial intermembrane space protein connected to respiratory chain assembly. J Mol Biol. 2014 Feb 20;426(4):908-20 doi: 10.1016/j.jmb.2013.12.001 PMID: 24333015
     
  • Pernitzsch SR, Tirier SM, Beier D, Sharma CM. A variable homopolymeric G-repeat defines small RNA-mediated posttranscriptional regulation of a chemotaxis receptor in Helicobacter pylori. Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):E501-10 doi: 10.1073/pnas.1315152111 PMID: 24474799; PMCID: PMC3910625
     
  • Remmele CW, Xian Y, Albrecht M, Faulstich M, Fraunholz M, Heinrichs E, Dittrich MT, Müller T, Reinhardt R, Rudel T. Transcriptional landscape and essential genes of Neisseria gonorrhoeae. Nucleic Acids Res. 2014;42(16):10579-95 doi: 10.1093/nar/gku762 PMID: 25143534; PMCID: PMC4176332

  • Sibilski C, Mueller T, Kollipara L, Zahedi RP, Rapp UR, Rudel T, Baljuls A. Tyr728 in the kinase domain of the murine kinase suppressor of RAS 1 regulates binding and activation of the mitogen-activated protein kinase kinase. J Biol Chem. 2013 Dec 6;288(49):35237-52 doi: 10.1074/jbc.M113.490235 PMID: 24158441; PMCID: PMC3853273
     
  • Mehlitz A, Rudel T. Modulation of host signaling and cellular responses by Chlamydia. Cell Commun Signal. 2013 Nov 22;11:90 doi: 10.1186/1478-811X-11-90 PMID: 24267514; PMCID: PMC4222901
     
  • Fraunholz M, Bernhardt J, Schuldes J, Daniel R, Hecker M, Sinha B. Complete Genome Sequence of Staphylococcus aureus 6850, a Highly Cytotoxic and Clinically Virulent Methicillin-Sensitive Strain with Distant Relatedness to Prototype Strains. Genome Announc. 2013 Sep 26;1(5). pii: e00775-13 doi: 10.1128/genomeA.00775-13 PMID: 24072870; PMCID: PMC3784790
     
  • Rudel TK. The national determinants of deforestation in sub-Saharan Africa. Philos Trans R Soc Lond B Biol Sci. 2013 Jul 22;368(1625):20120405 doi: 10.1098/rstb.2012.0405 PMID: 23878341; PMCID: PMC3720032
     
  • Eisenreich W, Heesemann J, Rudel T, Goebel W. Metabolic host responses to infection by intracellular bacterial pathogens. Front Cell Infect Microbiol. 2013 Jul 9;3:24 doi: 10.3389/fcimb.2013.00024 PMID: 23847769; PubMed Central PMCID: PMC3705551
     
  • Ratzka C, Gross R, Feldhaar H. Gene expression analysis of the endosymbiont-bearing midgut tissue during ontogeny of the carpenter ant Camponotus floridanus. J Insect Physiol. 2013 Jun 59(6):611-23. doi: 10.1016/j.jinsphys.2013.03.011 PMID: 23570961
     
  • Bauer S, Endres M, Lange M, Schmidt T, Schumbrutzki C, Sickmann A, Beier D. Novel function assignment to a member of the essential HP1043 response regulator family of epsilon-proteobacteria. Microbiology. 2013 May 159(Pt 5):880-9. doi: 10.1099/mic.0.066548-0 PMID: 23475951
     
  • Prusty BK, Siegl C, Hauck P, Hain J, Korhonen SJ, Hiltunen-Back E, Puolakkainen M, Rudel T. Chlamydia trachomatis infection induces replication of latent HHV-6. PLoS One. 2013 Apr 19;8(4):e61400 doi: 10.1371/journal.pone.0061400 PMID: 23620749; PMCID: PMC3631192
     
  • Ott C, Utech M, Goetz M, Rudel T, Kozjak-Pavlovic V. Requirements for the import of neisserial Omp85 into the outer membrane of human mitochondria. Biosci Rep. 2013 Mar 13;33(2):e00028 doi: 10.1042/BSR20130007 PMID: 23368846; PMCID: PMC3596097
     
  • Zeth K, Kozjak-Pavlovic V, Faulstich M, Fraunholz M, Hurwitz R, Kepp O, Rudel T. Structure and function of the PorB porin from disseminating Neisseria gonorrhoeae. Biochem J. 2013 Feb 1;449(3):631-42 doi: 10.1042/BJ20121025Erratum in: Biochem J.
     
  • Castro IC, Breiling A, Luetkenhaus K, Ceteci F, Hausmann S, Kress S, Lyko F, Rudel T, Rapp UR. MYC-induced epigenetic activation of GATA4 in lung adenocarcinoma. Mol Cancer Res. 2013 Feb 11(2):161-72. doi: 10.1158/1541-7786.MCR-12-0414-T PMID: 23239811
     
  • Yevsa T, Ebensen T, Fuchs B, Zygmunt B, Libanova R, Gross R, Schulze K, Guzmán CA. Development and characterization of attenuated metabolic mutants of Bordetella bronchiseptica for applications in vaccinology. Environ Microbiol. 2013 Jan 15(1):64-76. doi: 10.1111/j.1462-2920.2012.02779.x PMID: 22676396
     
  • Prusty BK, Krohne G, Rudel T. Reactivation of chromosomally integrated human herpesvirus-6 by telomeric circle formation. PLoS Genet. "2013;9(12):e1004033 doi: 10.1371/journal.pgen.1004033 PMID: 24367281; PMCID: PMC3868596
     
  • Kato H, Lu Q, Rapaport D, Kozjak-Pavlovic V. Tom70 is essential for PINK1 import into mitochondria. PLoS One. "2013;8(3):e58435 doi: 10.1371/journal.pone.0058435 PMID: 23472196; PMCID: PMC3589387
     
  • Faulstich M, Böttcher JP, Meyer TF, Fraunholz M, Rudel T. Pilus phase variation switches gonococcal adherence to invasion by caveolin-1-dependent host cell signaling. PLoS Pathog. "2013;9(5):e1003373 doi: 10.1371/journal.ppat.1003373 PMID: 23717204; PMCID: PMC3662692

  • Rajalingam K, Rudel T. Prohibiting CRAF/MAPK activation with rocaglamides. Chem Biol. 2012 Sep 21;19(9):1077-8 doi: 10.1016/j.chembiol.2012.09.004PubMed PMID: 22999872
     
  • Baljuls A, Beck M, Oenel A, Robubi A, Kroschewski R, Hekman M, Rudel T, Rapp UR. The tumor suppressor DiRas3 forms a complex with H-Ras and C-RAF proteins and regulates localization, dimerization, and kinase activity of C-RAF. J Biol Chem. 2012 Jun 29;287(27):23128-40 doi: 10.1074/jbc.M112.343780 PMID: 22605333; PMCID: PMC3391090
     
  • Ratzka C, Gross R, Feldhaar H. Endosymbiont Tolerance and Control within Insect Hosts. Insects. 2012 Jun 15;3(2):553-72 doi: 10.3390/insects3020553 PMID: 26466544; PMCID: PMC4553611
     
  • Fraunholz M, Sinha B. Intracellular Staphylococcus aureus: live-in and let die. Front Cell Infect Microbiol. 2012 Apr 24;2:43 doi: 10.3389/fcimb.2012.00043 PMID: 22919634; PMCID: PMC3417557
     
  • Ott C, Ross K, Straub S, Thiede B, Götz M, Goosmann C, Krischke M, Mueller MJ, Krohne G, Rudel T, Kozjak-Pavlovic V. Sam50 functions in mitochondrial intermembrane space bridging and biogenesis of respiratory complexes. Mol Cell Biol. 2012 Mar 32(6):1173-88. doi: 10.1128/MCB.06388-11 PMID: 22252321; PMCID: PMC3295012
     
  • Rudel T. To die or not to die: Shigella has an answer. Cell Host Microbe. 2012 Mar 15;11(3):219-21 doi: 10.1016/j.chom.2012.02.004 PMID: 22423960
     
  • Ratzka C, Förster F, Liang C, Kupper M, Dandekar T, Feldhaar H, Gross R. Molecular characterization of antimicrobial peptide genes of the carpenter ant Camponotus floridanus. PLoS One. "2012;7(8):e43036 doi: 10.1371/journal.pone.0043036 PMID: 22912782; PMCID: PMC3415428
     
  • Prusty BK, Böhme L, Bergmann B, Siegl C, Krause E, Mehlitz A, Rudel T. Imbalanced oxidative stress causes chlamydial persistence during non-productive human herpes virus co-infection. PLoS One. "2012;7(10):e47427 doi: 10.1371/journal.pone.0047427 PMID: 23077614; PMCID: PMC3471814
     
  • Krueger B, Friedrich T, Förster F, Bernhardt J, Gross R, Dandekar T. Different evolutionary modifications as a guide to rewire two-component systems. Bioinform Biol Insights. "2012;6:97-128 doi: 10.4137/BBI.S9356 PMID: 22586357; PMCID: PMC3348925
     
  • Geiger T, Francois P, Liebeke M, Fraunholz M, Goerke C, Krismer B, Schrenzel J, Lalk M, Wolz C. The stringent response of Staphylococcus aureus and its impact on survival after phagocytosis through the induction of intracellular PSMs expression. PLoS Pathog. "2012;8(11):e1003016 doi: 10.1371/journal.ppat.1003016 PMID: 23209405; PMCID: PMC3510239
     
  • Albrecht M, Sharma CM, Dittrich MT, Müller T, Reinhardt R, Vogel J, Rudel T. The transcriptional landscape of Chlamydia pneumoniae. Genome Biol. 2011 Oct 11;12(10):R98 doi: 10.1186/gb-2011-12-10-r98 PMID: 21989159; PMCID: PMC3333780
     
  • Sharma M, Machuy N, Böhme L, Karunakaran K, Mäurer AP, Meyer TF, Rudel T. HIF-1alpha is involved in mediating apoptosis resistance to Chlamydia trachomatis-infected cells. Cell Microbiol. 2011 Oct 13(10):1573-85. doi: 10.1111/j.1462-5822.2011.01642.x PMID: 21824245
     
  • Ratzka C, Liang C, Dandekar T, Gross R, Feldhaar H. Immune response of the ant Camponotus floridanus against pathogens and its obligate mutualistic endosymbiont. Insect Biochem Mol Biol. 2011 Aug 41(8):529-36. doi: 10.1016/j.ibmb.2011.03.002 PMID: 21440063
     
  • Kozjak-Pavlovic V, Ott C, Götz M, Rudel T. Neisserial Omp85 protein is selectively recognized and assembled into functional complexes in the outer membrane of human mitochondria. J Biol Chem. 2011 Jul 29;286(30):27019-26 doi: 10.1074/jbc.M111.232249 PMID: 21652692; PMCID: PMC3143660
     
  • Ziegler P, Teller S, Ha NH, Giese B, Fraunholz M, Walther R. Phosphoproteomic identification of a PDX-1/14-3-3ε interaction in pancreatic beta cells. Horm Metab Res. 2011 Mar 43(3):165-70. doi: 10.1055/s-0030-1270526 PMID: 21287435
     
  • Fritsch F, Mauder N, Williams T, Weiser J, Oberle M, Beier D. The cell envelope stress response mediated by the LiaFSRLm three-component system of Listeria monocytogenes is controlled via the phosphatase activity of the bifunctional histidine kinase LiaSLm. Microbiology. 2011 Feb 157(Pt 2):373-86. doi: 10.1099/mic.0.044776-0 PMID: 21030435
     
  • Giese B, Glowinski F, Paprotka K, Dittmann S, Steiner T, Sinha B, Fraunholz MJ. Expression of alpha-toxin by Staphylococcus aureus mediates escape from phago-endosomes of human epithelial and endothelial cells in the presence of β-toxin. Cell Microbiol. 2011 Feb 13(2):316-29. doi: 10.1111/j.1462-5822.2010.01538.x PMID: 20946243
     
  • Cornfine S, Himmel M, Kopp P, El Azzouzi K, Wiesner C, Krüger M, Rudel T, Linder S. The kinesin KIF9 and reggie/flotillin proteins regulate matrix degradation by macrophage podosomes. Mol Biol Cell. 2011 Jan 15;22(2):202-15 doi: 10.1091/mbc.E10-05-0394 PMID: 21119006; PMCID: PMC3020916
     
  • Karunakaran K, Mehlitz A, Rudel T. Evolutionary conservation of infection-induced cell death inhibition among Chlamydiales. PLoS One. "2011;6(7):e22528 doi: 10.1371/journal.pone.0022528 PMID: 21799887; PMCID: PMC3142178
     
  • Prusty BK, Karlas A, Meyer TF, Rudel T. Genome-wide RNAi screen for viral replication in mammalian cell culture. Methods Mol Biol. "2011;721:383-95 doi: 10.1007/978-1-61779-037-9_24 PMID: 21431699
     
  • Meyfroidt P, Rudel TK, Lambin EF. Forest transitions, trade, and the global displacement of land use. Proc Natl Acad Sci U S A. 2010 Dec 7;107(49):20917-22. doi: 10.1073/pnas.1014773107 PMID: 21078977; PMCID: PMC3000287
     
  • Stoll S, Feldhaar H, Fraunholz MJ, Gross R. Bacteriocyte dynamics during development of a holometabolous insect, the carpenter ant Camponotus floridanus. BMC Microbiol. 2010 Dec 1;10:308 doi: 10.1186/1471-2180-10-308 PMID: 21122115; PMCID: PMC3009655
     
  • Wolf G, Hessabi B, Karkour A, Henrion U, Dahlhaus M, Ostmann A, Giese B, Fraunholz M, Grabarczyk P, Jack R, Walther R. The activation of the rat insulin gene II by BETA2 and PDX-1 in rat insulinoma cells is repressed by Pax6. Mol Endocrinol. 2010 Dec 24(12):2331-42. doi: 10.1210/me.2009-0220 PMID: 20943817
     
  • Rändler C, Matthes R, McBain AJ, Giese B, Fraunholz M, Sietmann R, Kohlmann T, Hübner NO, Kramer A. A three-phase in-vitro system for studying Pseudomonas aeruginosa adhesion and biofilm formation upon hydrogel contact lenses. BMC Microbiol. 2010 Nov 9;10:282 doi: 10.1186/1471-2180-10-282 PMID: 21062489; PMCID: PMC2997771
     
  • Paprotka K, Giese B, Fraunholz MJ. Codon-improved fluorescent proteins in investigation of Staphylococcus aureus host pathogen interactions. J Microbiol Methods. 2010 Oct 83(1):82-6. doi: 10.1016/j.mimet.2010.07.022 PMID: 20708040
     
  • Rudel T, Kepp O, Kozjak-Pavlovic V. Interactions between bacterial pathogens and mitochondrial cell death pathways. Nat Rev Microbiol. 2010 Oct 8(10):693-705. doi: 10.1038/nrmicro2421 PMID: 20818415
     
  • Sievers C, Billig G, Gottschalk K, Rudel T. Prohibitins are required for cancer cell proliferation and adhesion. PLoS One. 2010 Sep 14;5(9):e12735 doi: 10.1371/journal.pone.0012735 PMID: 20856874; PMCID: PMC2939069
     
  • Böhme L, Albrecht M, Riede O, Rudel T. Chlamydia trachomatis-infected host cells resist dsRNA-induced apoptosis. Cell Microbiol. 2010 Sep 1;12(9):1340-51 doi: 10.1111/j.1462-5822.2010.01473.x PMID: 20482554
     
  • Lam TT, Giese B, Chikkaballi D, Kühn A, Wolber W, Pane-Farre J, Schäfer D, Engelmann S, Fraunholz M, Sinha B. Phagolysosomal integrity is generally maintained after Staphylococcus aureus invasion of nonprofessional phagocytes but is modulated by strain 6850. Infect Immun. 2010 Aug 78(8):3392-403. doi: 10.1128/IAI.00012-10 PMID: 20530231; PMCID: PMC2916288
     
  • Gross R, Keidel K, Schmitt K. Resemblance and divergence: the new members of the genus Bordetella. Med Microbiol Immunol. 2010 Aug 199(3):155-63. doi: 10.1007/s00430-010-0148-z PMID: 20390299
     
  • Prakash H, Albrecht M, Becker D, Kuhlmann T, Rudel T. Deficiency of XIAP leads to sensitization for Chlamydophila pneumoniae pulmonary infection and dysregulation of innate immune response in mice. J Biol Chem. 2010 Jun 25;285(26):20291-302 doi: 10.1074/jbc.M109.096297 PMID: 20427267; PMCID: PMC2888442
     
  • Köck K, Koenen A, Giese B, Fraunholz M, May K, Siegmund W, Hammer E, Völker U, Jedlitschky G, Kroemer HK, Grube M. Rapid modulation of the organic anion transporting polypeptide 2B1 (OATP2B1, SLCO2B1) function by protein kinase C-mediated internalization. J Biol Chem. 2010 Apr 9;285(15):11336-47 doi: 10.1074/jbc.M109.056457 PMID: 20159975; PMCID: PMC2857012
     
  • Kozjak-Pavlovic V, Ross K, Götz M, Goosmann C, Rudel T. A tag at the carboxy terminus prevents membrane integration of VDAC1 in mammalian mitochondria. J Mol Biol. 2010 Mar 19;397(1):219-32 doi: 10.1016/j.jmb.2010.01.047 PMID: 20117113
     
  • Gurumurthy RK, Mäurer AP, Machuy N, Hess S, Pleissner KP, Schuchhardt J, Rudel T, Meyer TF. A loss-of-function screen reveals Ras- and Raf-independent MEK-ERK signaling during Chlamydia trachomatis infection. Sci Signal. 2010 Mar 16;3(113):ra21 doi: 10.1126/scisignal.2000651 PMID: 20234004
     
  • Niu H, Kozjak-Pavlovic V, Rudel T, Rikihisa Y. Anaplasma phagocytophilum Ats-1 is imported into host cell mitochondria and interferes with apoptosis induction. PLoS Pathog. 2010 Feb 19;6(2):e1000774 doi: 10.1371/journal.ppat.1000774 PMID: 20174550; PMCID: PMC2824752
     
  • Sinha B, Fraunholz M. Staphylococcus aureus host cell invasion and post-invasion events. Int J Med Microbiol. 2010 Feb 300(2-3):170-5. doi: 10.1016/j.ijmm.2009.08.019 PMID: 19781990
     
  • Albrecht M, Sharma CM, Reinhardt R, Vogel J, Rudel T. Deep sequencing-based discovery of the Chlamydia trachomatis transcriptome. Nucleic Acids Res. 2010 Jan 38(3):868-77. doi: 10.1093/nar/gkp1032 PMID: 19923228; PMCID: PMC2817459
     
  • Rudel TK, Schneider L, Uriarte M, Turner BL 2nd, DeFries R, Lawrence D, Geoghegan J, Hecht S, Ickowitz A, Lambin EF, Birkenholtz T, Baptista S, Grau R. Agricultural intensification and changes in cultivated areas, 1970-2005. Proc Natl Acad Sci U S A. 2009 Dec 8;106(49):20675-80 doi: 10.1073/pnas.0812540106 PMID: 19955435; PMCID: PMC2791618
     
  • Rudel TK, Defries R, Asner GP, Laurance WF. Changing drivers of deforestation and new opportunities for conservation. Conserv Biol. 2009 Dec 23(6):1396-405. doi: 10.1111/j.1523-1739.2009.01332.x PMID: 20078640
     
  • Asner GP, Rudel TK, Aide TM, Defries R, Emerson R. A contemporary assessment of change in humid tropical forests. Conserv Biol. 2009 Dec 23(6):1386-95. doi: 10.1111/j.1523-1739.2009.01333.x PMID: 20078639
     
  • Liang C, Schmid A, López-Sánchez MJ, Moya A, Gross R, Bernhardt J, Dandekar T. JANE: efficient mapping of prokaryotic ESTs and variable length sequence reads on related template genomes. BMC Bioinformatics. 2009 Nov 29;10:391 doi: 10.1186/1471-2105-10-391 PMID: 19943962; PMCID: PMC2789075
     
  • Böhme L, Rudel T. Host cell death machinery as a target for bacterial pathogens. Microbes Infect. 2009 Nov 11(13):1063-70. doi: 10.1016/j.micinf.2009.08.014 PMID: 19733679
     
  • Kozjak-Pavlovic V, Dian-Lothrop EA, Meinecke M, Kepp O, Ross K, Rajalingam K, Harsman A, Hauf E, Brinkmann V, Günther D, Herrmann I, Hurwitz R, Rassow J, Wagner R, Rudel T. Bacterial porin disrupts mitochondrial membrane potential and sensitizes host cells to apoptosis. PLoS Pathog. 2009 Oct 5(10):e1000629. doi: 10.1371/journal.ppat.1000629 PMID: 19851451; PMCID: PMC2759283
     
  • Jung M, Mollenkopf HJ, Grimm C, Wagner I, Albrecht M, Waller T, Pilarsky C, Johannsen M, Stephan C, Lehrach H, Nietfeld W, Rudel T, Jung K, Kristiansen G. MicroRNA profiling of clear cell renal cell cancer identifies a robust signature to define renal malignancy. J Cell Mol Med. 2009 Sep 13(9B):3918-28. doi: 10.1111/j.1582-4934.2009.00705.x PMID: 19228262; PMCID: PMC4516539
     
  • Giese B, Dittmann S, Paprotka K, Levin K, Weltrowski A, Biehler D, Lâm TT, Sinha B, Fraunholz MJ. Staphylococcal alpha-toxin is not sufficient to mediate escape from phagolysosomes in upper-airway epithelial cells. Infect Immun. 2009 Sep 77(9):3611-25. doi: 10.1128/IAI.01478-08 PMID: 19564384; PMCID: PMC2738027
     
  • Müller S, Götz M, Beier D. Histidine residue 94 is involved in pH sensing by histidine kinase ArsS of Helicobacter pylori. PLoS One. 2009 Sep 7;4(9):e6930 doi: 10.1371/journal.pone.0006930 PMID: 19759826; PMCID: PMC2736386
     
  • Gross R, Vavre F, Heddi A, Hurst GD, Zchori-Fein E, Bourtzis K. Immunity and symbiosis. Mol Microbiol. 2009 Sep 73(5):751-9. doi: 10.1111/j.1365-2958.2009.06820.x PMID: 19656293
     
  • Prakash H, Becker D, Böhme L, Albert L, Witzenrath M, Rosseau S, Meyer TF, Rudel T. cIAP-1 controls innate immunity to C. pneumoniae pulmonary infection. PLoS One. 2009 Aug 6;4(8):e6519 doi: 10.1371/journal.pone.0006519 PMID: 19657383; PMCID: PMC2716518
     
  • Galluzzi L, Aaronson SA, Abrams J, Alnemri ES, Andrews DW, Baehrecke EH, Bazan NG, Blagosklonny MV, Blomgren K, Borner C, Bredesen DE, Brenner C, Castedo M, Cidlowski JA, Ciechanover A, Cohen GM, De Laurenzi V, De Maria R, Deshmukh M, Dynlacht BD, El-Deiry WS, Flavell RA, Fulda S, Garrido C, Golstein P, Gougeon ML, Green DR, Gronemeyer H, Hajnóczky G, Hardwick JM, Hengartner MO, Ichijo H, Jäättelä M, Kepp O, Kimchi A, Klionsky DJ, Knight RA, Kornbluth S, Kumar S, Levine B, Lipton SA, Lugli E, Madeo F, Malomi W, Marine JC, Martin SJ, Medema JP, Mehlen P, Melino G, Moll UM, Morselli E, Nagata S, Nicholson DW, Nicotera P, Nuñez G, Oren M, Penninger J, Pervaiz S, Peter ME, Piacentini M, Prehn JH, Puthalakath H, Rabinovich GA, Rizzuto R, Rodrigues CM, Rubinsztein DC, Rudel T, Scorrano L, Simon HU, Steller H, Tschopp J, Tsujimoto Y, Vandenabeele P, Vitale I, Vousden KH, Youle RJ, Yuan J, Zhivotovsky B, Kroemer G. Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell Death Differ. 2009 Aug 16(8):1093-107. doi: 10.1038/cdd.2009.44 PMID: 19373242; PMCID: PMC2757140
     
  • Lechner M, Schmitt K, Bauer S, Hot D, Hubans C, Levillain E, Locht C, Lemoine Y, Gross R. Genomic island excisions in Bordetella petrii. BMC Microbiol. 2009 Jul 18;9:141 doi: 10.1186/1471-2180-9-141 PMID: 19615092; PMCID: PMC2717098
     
  • Rudel TK. How do people transform landscapes? A sociological perspective on suburban sprawl and tropical deforestation. AJS. 2009 Jul 115(1):129-54. PMID: 19852187
     
  • Stoll S, Feldhaar H, Gross R. Promoter characterization in the AT-rich genome of the obligate endosymbiont Candidatus Blochmannia floridanus. J Bacteriol. 2009 Jun 191(11):3747-51. doi: 10.1128/JB.00069-09 PMID: 19329646; PMCID: PMC2681919
     
  • Ross K, Rudel T, Kozjak-Pavlovic V. TOM-independent complex formation of Bax and Bak in mammalian mitochondria during TNFalpha-induced apoptosis. Cell Death Differ. 2009 May 16(5):697-707. doi: 10.1038/cdd.2008.194 PMID: 19165229
     
  • Kepp O, Gottschalk K, Churin Y, Rajalingam K, Brinkmann V, Machuy N, Kroemer G, Rudel T. Bim and Bmf synergize to induce apoptosis in Neisseria gonorrhoeae infection. PLoS Pathog. 2009 Mar 5(3):e1000348. doi: 10.1371/journal.ppat.1000348 PMID: 19300516; PMCID: PMC2654407
     
  • Sharma M, Rudel T. Apoptosis resistance in Chlamydia-infected cells: a fate worse than death? FEMS Immunol Med Microbiol. 2009 Mar 55(2):154-61. doi: 10.1111/j.1574-695X.2008.00515.x PMID: 19281566
     
  • Feldhaar H, Gross R. Insects as hosts for mutualistic bacteria. Int J Med Microbiol. 2009 Jan 299(1):1-8. doi: 10.1016/j.ijmm.2008.05.010 PMID: 18640072
     
  • Feldhaar H, Gross R. Genome degeneration affects both extracellular and intracellular bacterial endosymbionts. J Biol. "2009;8(3):31 doi: 10.1186/jbiol129 PMID: 19435469; PMCID: PMC2689433
     
  • Horvat A, Gross R. Molecular characterization of the BvgA response regulator of Bordetella holmesii. Microbiol Res. "2009;164(3):243-52 PMID: 17400438
     
  • Prusty BK, zur Hausen H, Schmidt R, Kimmel R, de Villiers EM. Transcription of HERV-E and HERV-E-related sequences in malignant and non-malignant human haematopoietic cells. Virology. 2008 Dec 5;382(1):37-45 doi: 10.1016/j.virol.2008.09.006 PMID: 18929381
     
  • Gross R, Guzman CA, Sebaihia M, dos Santos VA, Pieper DH, Koebnik R, Lechner M, Bartels D, Buhrmester J, Choudhuri JV, Ebensen T, Gaigalat L, Herrmann S, Khachane AN, Larisch C, Link S, Linke B, Meyer F, Mormann S, Nakunst D, Rückert C, Schneiker-Bekel S, Schulze K, Vorhölter FJ, Yevsa T, Engle JT, Goldman WE, Pühler A, Göbel UB, Goesmann A, Blöcker H, Kaiser O, Martinez-Arias R. The missing link: Bordetella petrii is endowed with both the metabolic versatility of environmental bacteria and virulence traits of pathogenic Bordetellae. BMC Genomics. 2008 Sep 30;9:449 doi: 10.1186/1471-2164-9-449 PMID: 18826580; PMCID: PMC2572626
     
  • Rajalingam K, Sharma M, Lohmann C, Oswald M, Thieck O, Froelich CJ, Rudel T. Mcl-1 is a key regulator of apoptosis resistance in Chlamydia trachomatis-infected cells. PLoS One. 2008 Sep 1;3(9):e3102 doi: 10.1371/journal.pone.0003102 PMID: 18769617; PMCID: PMC2518856
     
  • Mantei A, Rutz S, Janke M, Kirchhoff D, Jung U, Patzel V, Vogel U, Rudel T, Andreou I, Weber M, Scheffold A. siRNA stabilization prolongs gene knockdown in primary T lymphocytes. Eur J Immunol. 2008 Sep 38(9):2616-25. doi: 10.1002/eji.200738075 PMID: 18792414
     
  • Reder A, Höper D, Weinberg C, Gerth U, Fraunholz M, Hecker M. The Spx paralogue MgsR (YqgZ) controls a subregulon within the general stress response of Bacillus subtilis. Mol Microbiol. 2008 Sep 69(5):1104-20. doi: 10.1111/j.1365-2958.2008.06332.x PMID: 18643936
     
  • Mauder N, Williams T, Fritsch F, Kuhn M, Beier D. Response regulator DegU of Listeria monocytogenes controls temperature-responsive flagellar gene expression in its unphosphorylated state. J Bacteriol. 2008 Jul 190(13):4777-81. doi: 10.1128/JB.00258-08 PMID: 18441066; PMCID: PMC2446787
     
  • Feldhaar H, Gross R. Immune reactions of insects on bacterial pathogens and mutualists. Microbes Infect. 2008 Jul 10(9):1082-8. doi: 10.1016/j.micinf.2008.07.010 PMID: 18672091
     
  • Wang JA, Meyer TF, Rudel T. Cytoskeleton and motor proteins are required for the transcytosis of Neisseria gonorrhoeae through polarized epithelial cells. Int J Med Microbiol. 2008 Apr 298(3-4):209-21. PMID: 17683982
     
  • Pande S, Jain N, Prusty BK, Bhambhani S, Gupta S, Sharma R, Batra S, Das BC. Human papillomavirus type 16 variant analysis of E6, E7, and L1 genes and long control region in biopsy samples from cervical cancer patients in north India. J Clin Microbiol. 2008 Mar 46(3):1060-6. doi: 10.1128/JCM.02202-07 PMID: 18199779; PMCID: PMC2268386
     
  • Paland N, Böhme L, Gurumurthy RK, Mäurer A, Szczepek AJ, Rudel T. Reduced display of tumor necrosis factor receptor I at the host cell surface supports infection with Chlamydia trachomatis. J Biol Chem. 2008 Mar 7;283(10):6438-48 doi: 10.1074/jbc.M708422200 PMID: 18167350
     
  • Kozjak-Pavlovic V, Ross K, Rudel T. Import of bacterial pathogenicity factors into mitochondria. Curr Opin Microbiol. 2008 Feb 11(1):9-14. doi: 10.1016/j.mib.2007.12.004 PMID: 18280201
     
  • Scholz M, Fraunholz MJ. A computational model of gene expression reveals early transcriptional events at the subtelomeric regions of the malaria parasite, Plasmodium falciparum. Genome Biol. " 2008;9(5):R88 doi: 10.1186/gb-2008-9-5-r88 PMID: 18505551; PMCID: PMC2441474
     
  • Beier D, Gross R. The BvgS/BvgA phosphorelay system of pathogenic Bordetellae: structure, function and evolution. Adv Exp Med Biol. "2008;631:149-60 doi: 10.1007/978-0-387-78885-2_10 PMID: 18792687
     
  • Schmidt F, Hustoft HK, Strozynski M, Dimmler C, Rudel T, Thiede B. Quantitative proteome analysis of cisplatin-induced apoptotic Jurkat T cells by stable isotope labeling with amino acids in cell culture, SDS-PAGE, and LC-MALDI-TOF/TOF MS. Electrophoresis. 2007 Dec 28(23):4359-68. PMID: 17987630
     
  • Rechner C, Kühlewein C, Müller A, Schild H, Rudel T. Host glycoprotein Gp96 and scavenger receptor SREC interact with PorB of disseminating Neisseria gonorrhoeae in an epithelial invasion pathway. Cell Host Microbe. 2007 Dec 13;2(6):393-403 PMID: 18078691
     
  • Stojanovski D, Guiard B, Kozjak-Pavlovic V, Pfanner N, Meisinger C. Alternative function for the mitochondrial SAM complex in biogenesis of alpha-helical TOM proteins. J Cell Biol. 2007 Dec 3;179(5):881-93
     
  • Josenhans C, Beier D, Linz B, Meyer TF, Suerbaum S. Pathogenomics of helicobacter. Int J Med Microbiol. 2007 Nov 297(7-8):589-600. PMID: 17416549
     
  • Link S, Schmitt K, Beier D, Gross R. Identification and regulation of expression of a gene encoding a filamentous hemagglutinin-related protein in Bordetella holmesii. BMC Microbiol. 2007 Nov 7;7:100 PMID: 17988394; PMCID: PMC2225982
     
  • Feldhaar H, Straka J, Krischke M, Berthold K, Stoll S, Mueller MJ, Gross R. Nutritional upgrading for omnivorous carpenter ants by the endosymbiont Blochmannia. BMC Biol. 2007 Oct 30;5:48 PMID: 17971224; PMCID: PMC2206011
     
  • Satake A, Rudel TK. Modeling the forest transition: forest scarcity and ecosystem service hypotheses. Ecol Appl. 2007 Oct 17(7):2024-36. PMID: 17974339
     
  • Prusty BK, Hedau S, Singh A, Kar P, Das BC. Selective suppression of NF-kBp65 in hepatitis virus-infected pregnant women manifesting severe liver damage and high mortality. Mol Med. 2007 Sep Oct;13(9-10):518-26 PMID: 17660862; PMCID: PMC1933259
     
  • Rajalingam K, Oswald M, Gottschalk K, Rudel T. Smac/DIABLO is required for effector caspase activation during apoptosis in human cells. Apoptosis. 2007 Aug 12(8):1503-10. PMID: 17440818
     
  • Machuy N, Campa F, Thieck O, Rudel T. c-Abl-binding protein interacts with p21-activated kinase 2 (PAK-2) to regulate PDGF-induced membrane ruffles. J Mol Biol. 2007 Jul 20;370(4):620-32 PMID: 17543336
     
  • Kozjak-Pavlovic V, Ross K, Benlasfer N, Kimmig S, Karlas A, Rudel T. Conserved roles of Sam50 and metaxins in VDAC biogenesis. EMBO Rep. 2007 Jun 8(6):576-82. PMID: 17510655; PMCID: PMC2002532
     
  • Sanjuán Szklarz LK, Kozjak-Pavlovic V, Vögtle FN, Chacinska A, Milenkovic D, Vogel S, Dürr M, Westermann B, Guiard B, Martinou JC, Borner C, Pfanner N, Meisinger C. Preprotein transport machineries of yeast mitochondrial outer membrane are not required for Bax-induced release of intermembrane space proteins. J Mol Biol. 2007 Apr 20;368(1):44-54 PMID: 17335847
     
  • Pflock M, Müller S, Beier D. The CrdRS (HP1365-HP1364) two-component system is not involved in ph-responsive gene regulation in the Helicobacter pylori Strains 26695 and G27. Curr Microbiol. 2007 Apr 54(4):320-4. PMID: 17375361
     
  • Pflock M, Bathon M, Schär J, Müller S, Mollenkopf H, Meyer TF, Beier D. The orphan response regulator HP1021 of Helicobacter pylori regulates transcription of a gene cluster presumably involved in acetone metabolism. J Bacteriol. 2007 Mar 189(6):2339-49. PMID: 17220217; PMCID: PMC1899378
     
  • Kepp O, Rajalingam K, Kimmig S, Rudel T. Bak and Bax are non-redundant during infection- and DNA damage-induced apoptosis. EMBO J. 2007 Feb 7;26(3):825-34 PMID: 17235284; PMCID: PMC1794390
     
  • Joseph B, Beier D. Global analysis of two-component gene regulation in H. pylori by mutation analysis and transcriptional profiling. Methods Enzymol. "2007;423:514-30 PMID: 17609149
     
  • Gupta A, Arora R, Gupta S, Prusty BK, Kailash U, Batra S, Das BC. Human papillomavirus DNA in urine samples of women with or without cervical cancer and their male partners compared with simultaneously collected cervical/penile smear or biopsy specimens. J Clin Virol. 2006 Nov 37(3):190-4. PMID: 16931139
     
  • Pflock M, Kennard S, Finsterer N, Beier D. Acid-responsive gene regulation in the human pathogen Helicobacter pylori. J Biotechnol. 2006 Oct 20;126(1):52-60. PMID: 16713649
     
  • Paland N, Rajalingam K, Machuy N, Szczepek A, Wehrl W, Rudel T. NF-kappaB and inhibitor of apoptosis proteins are required for apoptosis resistance of epithelial cells persistently infected with Chlamydophila pneumoniae. Cell Microbiol. 2006 Oct 8(10):1643-55. PMID: 16984419
     
  • Rajalingam K, Sharma M, Paland N, Hurwitz R, Thieck O, Oswald M, Machuy N, Rudel T. IAP-IAP complexes required for apoptosis resistance of C. trachomatis-infected cells. PLoS Pathog. 2006 Oct 2(10):e114. PMID: 17069460; PMCID: PMC1626104
     
  • Campa F, Machuy N, Klein A, Rudel T. A new interaction between Abi-1 and betaPIX involved in PDGF-activated actin cytoskeleton reorganisation. Cell Res. 2006 Sep 16(9):759-70. PMID: 16940963
     
  • Zientz E, Beyaert I, Gross R, Feldhaar H. Relevance of the endosymbiosis of Blochmannia floridanus and carpenter ants at different stages of the life cycle of the host. Appl Environ Microbiol. 2006 Sep 72(9):6027-33. PMID: 16957225; PMCID: PMC1563639
     
  • Meisinger C, Wiedemann N, Rissler M, Strub A, Milenkovic D, Schönfisch B, Müller H, Kozjak V, Pfanner N. Mitochondrial protein sorting: differentiation of beta-barrel assembly by Tom7-mediated segregation of Mdm10. J Biol Chem. 2006 Aug 11;281(32):22819-26 PMID: 16760475
     
  • Kühlewein C, Rechner C, Meyer TF, Rudel T. Low-phosphate-dependent invasion resembles a general way for Neisseria gonorrhoeae to enter host cells. Infect Immun. 2006 Jul 74(7):4266-73. PMID: 16790801; PMCID: PMC1489691
     
  • Kopp P, Lammers R, Aepfelbacher M, Woehlke G, Rudel T, Machuy N, Steffen W, Linder S. The kinesin KIF1C and microtubule plus ends regulate podosome dynamics in macrophages. Mol Biol Cell. 2006 Jun 17(6):2811-23. PMID: 16554367; PMCID: PMC1474789
     
  • Pflock M, Finsterer N, Joseph B, Mollenkopf H, Meyer TF, Beier D. Characterization of the ArsRS regulon of Helicobacter pylori, involved in acid adaptation. J Bacteriol. 2006 May 188(10):3449-62. PMID: 16672598; PubMed Central PMCID: PMC1482845
     
  • Beier D, Gross R. Regulation of bacterial virulence by two-component systems. Curr Opin Microbiol. 2006 Apr 9(2):143-52. PMID: 16481212
     
  • Hu K, Johnson J, Florens L, Fraunholz M, Suravajjala S, DiLullo C, Yates J, Roos DS, Murray JM. Cytoskeletal components of an invasion machine--the apical complex of Toxoplasma gondii. PLoS Pathog. 2006 Feb 2(2):e13. PMID: 16518471; PMCID: PMC1383488
     
  • Thiede B, Kretschmer A, Rudel T. Quantitative proteome analysis of CD95 (Fas/Apo-1)-induced apoptosis by stable isotope labeling with amino acids in cell culture, 2-DE and MALDI-MS. Proteomics. 2006 Jan 6(2):614-22. PMID: 16342138
     
  • Gaudermann P, Vogl I, Zientz E, Silva FJ, Moya A, Gross R, Dandekar T. Analysis of and function predictions for previously conserved hypothetical or putative proteins in Blochmannia floridanus. BMC Microbiol. 2006 Jan 9;6:1 PMID: 16401340; PMCID: PMC1360075
     
  • Müller S, Förster J, Beier D. Repeated sequence motifs in the Helicobacter pylori P1408 promoter do not affect its transcription. Microbiol Res. "2006;161(3):212-21 PMID: 16765837
     
  • Zientz E, Feldhaar H, Stoll S, Gross R. Insights into the microbial world associated with ants. Arch Microbiol. 2005 Dec 184(4):199-206. PMID: 16205909
     
  • Williams T, Joseph B, Beier D, Goebel W, Kuhn M. Response regulator DegU of Listeria monocytogenes regulates the expression of flagella-specific genes. FEMS Microbiol Lett. 2005 Nov 15;252(2):287-98 PMID: 16213668
     
  • Rajalingam K, Rudel T. Ras-Raf signaling needs prohibitin. Cell Cycle. 2005 Nov 4(11):1503-5. PMID: 16294014
     
  • Butzke D, Hurwitz R, Thiede B, Goedert S, Rudel T. Cloning and biochemical characterization of APIT, a new l-amino acid oxidase from Aplysia punctata. Toxicon. 2005 Oct 46(5):479-89. PMID: 16153453
     
  • Pflock M, Kennard S, Delany I, Scarlato V, Beier D. Acid-induced activation of the urease promoters is mediated directly by the ArsRS two-component system of Helicobacter pylori. Infect Immun. 2005 Oct 73(10):6437-45. PMID: 16177315; PMCID: PMC1230922
     
  • Jimenez-Pearson MA, Delany I, Scarlato V, Beier D. Phosphate flow in the chemotactic response system of Helicobacter pylori. Microbiology. 2005 Oct 151(Pt 10):3299-311. PMID: 16207913
     
  • Fraunholz MJ. Systems biology in malaria research. Trends Parasitol. 2005 Sep 21(9):393-5. PMID: 16043412
     
  • Sanjuán Szklarz LK, Guiard B, Rissler M, Wiedemann N, Kozjak V, van der Laan M, Lohaus C, Marcus K, Meyer HE, Chacinska A, Pfanner N, Meisinger C. Inactivation of the mitochondrial heat shock protein zim17 leads to aggregation of matrix hsp70s followed by pleiotropic effects on morphology and protein biogenesis. J Mol Biol. 2005 Aug 5;351(1):206-18 PMID: 15992824
     
  • Rajalingam K, Wunder C, Brinkmann V, Churin Y, Hekman M, Sievers C, Rapp UR, Rudel T. Prohibitin is required for Ras-induced Raf-MEK-ERK activation and epithelial cell migration. Nat Cell Biol. 2005 Aug 7(8):837-43. PMID: 16041367
     
  • Arora R, Kumar A, Prusty BK, Kailash U, Batra S, Das BC. Prevalence of high-risk human papillomavirus (HR-HPV) types 16 and 18 in healthy women with cytologically negative Pap smear. Eur J Obstet Gynecol Reprod Biol. 2005 Jul 1;121(1):104-9 PMID: 15950365
     
  • Stübs D, Fuchs TM, Schneider B, Bosserhoff A, Gross R. Identification and regulation of cold-inducible factors of Bordetella bronchiseptica. Microbiology. 2005 Jun 151(Pt 6):1895-909. PMID: 15941997
     
  • Prusty BK, Husain SA, Das BC. Constitutive activation of nuclear factor -kB: preferntial homodimerization of p50 subunits in cervical carcinoma. Front Biosci. 2005 May 1;10:1510-9 PMID: 15769641
     
  • Schär J, Sickmann A, Beier D. Phosphorylation-independent activity of atypical response regulators of Helicobacter pylori. J Bacteriol. 2005 May 187(9):3100-9. PMID: 15838037; PMCID: PMC1082831
     
  • Williams T, Bauer S, Beier D, Kuhn M. Construction and characterization of Listeria monocytogenes mutants with in-frame deletions in the response regulator genes identified in the genome sequence. Infect Immun. 2005 May 73(5):3152-9. PMID: 15845524; PMCID: PMC1087338
     
  • Thiede B, Treumann A, Kretschmer A, Söhlke J, Rudel T. Shotgun proteome analysis of protein cleavage in apoptotic cells. Proteomics. 2005 May 5(8):2123-30. PMID: 15846839
     
  • Fowler T, Bamberg S, Möller P, Klenk HD, Meyer TF, Becker S, Rudel T. Inhibition of Marburg virus protein expression and viral release by RNA interference. J Gen Virol. 2005 Apr 86(Pt 4):1181-8. PMID: 15784912
     
  • Machuy N, Thiede B, Rajalingam K, Dimmler C, Thieck O, Meyer TF, Rudel T. A global approach combining proteome analysis and phenotypic screening with RNA interference yields novel apoptosis regulators. Mol Cell Proteomics. 2005 Jan 4(1):44-55. PMID: 15567892
     
  • Jimenez-Pearson MA, Dietz P, Beier D. Protein-protein interaction of HP137 with histidine kinase HP244 does not contribute to flagellar regulation in Helicobacter pylori. Microbiol Res. "2005;160(3):299-305 PMID: 16035242
     
  • Middendorf B, Stubs D, Guiso N, Deppisch H, Gross R, Fuchs TM. Phg, a novel member of the autotransporter family present in Bordetella species. Microbiol Res. "2005;160(3):329-36 PMID: 16035245
     
  • Zientz E, Dandekar T, Gross R. Metabolic interdependence of obligate intracellular bacteria and their insect hosts. Microbiol Mol Biol Rev. 2004 Dec 68(4):745-70. PMID: 15590782; PMCID: PMC539007
     
  • Gerlach G, Janzen S, Beier D, Gross R. Functional characterization of the BvgAS two-component system of Bordetella holmesii. Microbiology. 2004 Nov 150(Pt 11):3715-29. PMID: 15528658
     
  • Chacinska A, Pfannschmidt S, Wiedemann N, Kozjak V, Sanjuán Szklarz LK, Schulze-Specking A, Truscott KN, Guiard B, Meisinger C, Pfanner N. Essential role of Mia40 in import and assembly of mitochondrial intermembrane space proteins. EMBO J. 2004 Oct 1;23(19):3735-46 PMID: 15359280; PMCID: PMC522791
     
  • Thiede B, Rudel T. Proteome analysis of apoptotic cells. Mass Spectrom Rev. 2004 Sep Oct;23(5):333-49. PMID: 15264233
     
  • Meisinger C, Rissler M, Chacinska A, Szklarz LK, Milenkovic D, Kozjak V, Schönfisch B, Lohaus C, Meyer HE, Yaffe MP, Guiard B, Wiedemann N, Pfanner N. The mitochondrial morphology protein Mdm10 functions in assembly of the preprotein translocase of the outer membrane. Dev Cell. 2004 Jul 7(1):61-71. PMID: 15239954
     
  • Wolschin F, Hölldobler B, Gross R, Zientz E. Replication of the endosymbiotic bacterium Blochmannia floridanus is correlated with the developmental and reproductive stages of its ant host. Appl Environ Microbiol. 2004 Jul 70(7):4096-102. PMID: 15240288; PMCID: PMC444795
     
  • Butzke D, Machuy N, Thiede B, Hurwitz R, Goedert S, Rudel T. Hydrogen peroxide produced by Aplysia ink toxin kills tumor cells independent of apoptosis via peroxiredoxin I sensitive pathways. Cell Death Differ. 2004 Jun 11(6):608-17. PMID: 14765133
     
  • Harb OS, Chatterjee B, Fraunholz MJ, Crawford MJ, Nishi M, Roos DS. Multiple functionally redundant signals mediate targeting to the apicoplast in the apicomplexan parasite Toxoplasma gondii. Eukaryot Cell. 2004 Jun 3(3):663-74. PMID: 15189987; PMCID: PMC420125
     
  • Milenkovic D, Kozjak V, Wiedemann N, Lohaus C, Meyer HE, Guiard B, Pfanner N, Meisinger C. Sam35 of the mitochondrial protein sorting and assembly machinery is a peripheral outer membrane protein essential for cell viability. J Biol Chem. 2004 May 21;279(21):22781-5 PMID: 15067005
     
  • Pflock M, Dietz P, Schär J, Beier D. Genetic evidence for histidine kinase HP165 being an acid sensor of Helicobacter pylori. FEMS Microbiol Lett. 2004 May 1;234(1):51-61 PMID: 15109719
     
  • Machuy N, Rajalingam K, Rudel T. Requirement of caspase-mediated cleavage of c-Abl during stress-induced apoptosis. Cell Death Differ. 2004 Mar 11(3):290-300. PMID: 14657961
     
  • Ralph SA, van Dooren GG, Waller RF, Crawford MJ, Fraunholz MJ, Foth BJ, Tonkin CJ, Roos DS, McFadden GI. Tropical infectious diseases: metabolic maps and functions of the Plasmodium falciparum apicoplast. Nat Rev Microbiol. 2004 Mar 2(3):203-16. PMID: 15083156
     
  • Walduck A, Rudel T, Meyer TF. Proteomic and gene profiling approaches to study host responses to bacterial infection. Curr Opin Microbiol. 2004 Feb 7(1):33-8. PMID: 15036137
     
  • Kozjak V, Wiedemann N, Milenkovic D, Lohaus C, Meyer HE, Guiard B, Meisinger C, Pfanner N. An essential role of Sam50 in the protein sorting and assembly machinery of the mitochondrial outer membrane. J Biol Chem. 2003 Dec 5;278(49):48520-3 PMID: 14570913
     
  • Panthel K, Dietz P, Haas R, Beier D. Two-component systems of Helicobacter pylori contribute to virulence in a mouse infection model. Infect Immun. 2003 Sep 71(9):5381-5. PMID: 12933888; PMCID: PMC187308
     
  • Gil R, Silva FJ, Zientz E, Delmotte F, Gonzalez-Candelas F, Latorre A, Rausell C, Kamerbeek J, Gadau J, Hölldobler B, van Ham RC, Gross R, Moya A. The genome sequence of Blochmannia floridanus: comparative analysis of reduced genomes. Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9388-93 PMID: 12886019; PMCID: PMC170928
     
  • Wiedemann N, Kozjak V, Chacinska A, Schönfisch B, Rospert S, Ryan MT, Pfanner N, Meisinger C. Machinery for protein sorting and assembly in the mitochondrial outer membrane. Nature. 2003 Jul 31;424(6948):565-71 PMID: 12891361
     
  • Gross R, Hacker J, Goebel W. The Leopoldina international symposium on parasitism, commensalism and symbiosis--common themes, different outcome. Mol Microbiol. 2003 Mar 47(6):1749-58. PMID: 12622826
     
  • Wiedemann N, Kozjak V, Prinz T, Ryan MT, Meisinger C, Pfanner N, Truscott KN. Biogenesis of yeast mitochondrial cytochrome c: a unique relationship to the TOM machinery. J Mol Biol. 2003 Mar 21;327(2):465-74 PMID: 12628251
     
  • Bahl A, Brunk B, Crabtree J, Fraunholz MJ, Gajria B, Grant GR, Ginsburg H, Gupta D, Kissinger JC, Labo P, Li L, Mailman MD, Milgram AJ, Pearson DS, Roos DS, Schug J, Stoeckert CJ Jr, Whetzel P. PlasmoDB: the Plasmodium genome resource. A database integrating experimental and computational data. Nucleic Acids Res. 2003 Jan 1;31(1):212-5 PMID: 12519984; PMCID: PMC165528
     
  • Foth BJ, Ralph SA, Tonkin CJ, Struck NS, Fraunholz M, Roos DS, Cowman AF, McFadden GI. Dissecting apicoplast targeting in the malaria parasite Plasmodium falciparum. Science. 2003 Jan 31;299(5607):705-8 PMID: 12560551
     
  • Fraunholz MJ, Roos DS. PlasmoDB: exploring genomics and post-genomics data of the malaria parasite, Plasmodium falciparum. Redox Rep. "2003;8(5):317-20. PMID: 14962373
     
  • Kissinger JC, Brunk BP, Crabtree J, Fraunholz MJ, Gajria B, Milgram AJ, Pearson DS, Schug J, Bahl A, Diskin SJ, Ginsburg H, Grant GR, Gupta D, Labo P, Li L, Mailman MD, McWeeney SK, Whetzel P, Stoeckert CJ, Roos DS. The Plasmodium genome database. Nature. 2002 Oct 3;419(6906):490-2 PMID: 12368860
     
  • Gardner MJ, Hall N, Fung E, White O, Berriman M, Hyman RW, Carlton JM, Pain A, Nelson KE, Bowman S, Paulsen IT, James K, Eisen JA, Rutherford K, Salzberg SL, Craig A, Kyes S, Chan MS, Nene V, Shallom SJ, Suh B, Peterson J, Angiuoli S, Pertea M, Allen J, Selengut J, Haft D, Mather MW, Vaidya AB, Martin DM, Fairlamb AH, Fraunholz MJ, Roos DS, Ralph SA, McFadden GI, Cummings LM, Subramanian GM, Mungall C, Venter JC, Carucci DJ, Hoffman SL, Newbold C, Davis RW, Fraser CM, Barrell B. Genome sequence of the human malaria parasite Plasmodium falciparum. Nature. 2002 Oct 3;419(6906):498-511 PMID: 12368864; PMCID: PMC3836256
     
  • Sauer C, Dudaczek D, Hölldobler B, Gross R. Tissue localization of the endosymbiotic bacterium Candidatus Blochmannia floridanus in adults and larvae of the carpenter ant Camponotus floridanus. Appl Environ Microbiol. 2002 Sep 68(9):4187-93. PMID: 12200264; PMCID: PMC124124
     
  • Thiede B, Siejak F, Dimmler C, Rudel T. Prediction of translocation and cleavage of heterogeneous ribonuclear proteins and Rho guanine nucleotide dissociation inhibitor 2 during apoptosis by subcellular proteome analysis. Proteomics. 2002 Aug 2(8):996-1006. PMID: 12203895
     
  • Bock A, Gross R. The unorthodox histidine kinases BvgS and EvgS are responsive to the oxidation status of a quinone electron carrier. Eur J Biochem. 2002 Jul 269(14):3479-84. PMID: 12135487
     
  • König J, Bock A, Perraud AL, Fuchs TM, Beier D, Gross R. Regulatory factors of Bordetella pertussis affecting virulence gene expression. J Mol Microbiol Biotechnol. 2002 May 4(3):197-203. PMID: 11931547
     
  • Matrajt M, Nishi M, Fraunholz MJ, Peter O, Roos DS. Amino-terminal control of transgenic protein expression levels in Toxoplasma gondii. Mol Biochem Parasitol. 2002 Apr 9;120(2):285-9 PMID: 11897133
     
  • Müller A, Rassow J, Grimm J, Machuy N, Meyer TF, Rudel T. VDAC and the bacterial porin PorB of Neisseria gonorrhoeae share mitochondrial import pathways. EMBO J. 2002 Apr 15;21(8):1916-29 PMID: 11953311; PMCID: PMC125974
     
  • Dietz P, Gerlach G, Beier D. Identification of target genes regulated by the two-component system HP166-HP165 of Helicobacter pylori. J Bacteriol. 2002 Jan 184(2):350-62. PMID: 11751811; PMCID: PMC139590
     
  • Bahl A, Brunk B, Coppel RL, Crabtree J, Diskin SJ, Fraunholz MJ, Grant GR, Gupta D, Huestis RL, Kissinger JC, Labo P, Li L, McWeeney SK, Milgram AJ, Roos DS, Schug J, Stoeckert CJ Jr. PlasmoDB: the Plasmodium genome resource. An integrated database providing tools for accessing, analyzing and mapping expression and sequence data (both finished and unfinished). Nucleic Acids Res. 2002 Jan 1;30(1):87-90 PMID: 11752262; PMCID: PMC99106
     
  • Roos DS, Crawford MJ, Donald RG, Fraunholz M, Harb OS, He CY, Kissinger JC, Shaw MK, Striepen B. Mining the Plasmodium genome database to define organellar function: what does the apicoplast do? Philos Trans R Soc Lond B Biol Sci. 2002 Jan 29;357(1417):35-46 PMID: 11839180; PMCID: PMC1692924
     
  • Rajalingam K, Al-Younes H, Müller A, Meyer TF, Szczepek AJ, Rudel T. Epithelial cells infected with Chlamydophila pneumoniae (Chlamydia pneumoniae) are resistant to apoptosis. Infect Immun. 2001 Dec 69(12):7880-8. PMID: 11705971; PMCID: PMC98885
     
  • Popp A, Billker O, Rudel T. Signal transduction pathways induced by virulence factors of Neisseria gonorrhoeae. Int J Med Microbiol. 2001 Sep 291(4):307-14. PMID: 11680791
     
  • Müller A, Rudel T. Modification of host cell apoptosis by viral and bacterial pathogens. Int J Med Microbiol. 2001 Aug 291(3):197-207. PMID: 11554560
     
  • Thiede B, Dimmler C, Siejak F, Rudel T. Predominant identification of RNA-binding proteins in Fas-induced apoptosis by proteome analysis. J Biol Chem. 2001 Jul 13;276(28):26044-50 PMID: 11352910
     
  • Al-Younes HM, Rudel T, Brinkmann V, Szczepek AJ, Meyer TF. Low iron availability modulates the course of Chlamydia pneumoniae infection. Cell Microbiol. 2001 Jun 3(6):427-37. PMID: 11422085
     
  • Douglas S, Zauner S, Fraunholz M, Beaton M, Penny S, Deng LT, Wu X, Reith M, Cavalier-Smith T, Maier UG. The highly reduced genome of an enslaved algal nucleus. Nature. 2001 Apr 26;410(6832):1091-6 PMID: 11323671
     
  • Kamradt T, Rudel T, Englich S, Schaible UE. Institution profile: the Max-Planck-Institute for Infection biology and German Center for Rheumatological Research. Trends Microbiol. 2001 Feb 9(2):93-4. PMID: 11173249
     
  • Kamradt T, Rudel T, Selbach M, Schaible UE. A new home for infection research. Trends Microbiol. 2001 Feb 9(2):54-6. PMID: 11286190
     
  • Lorenzen DR, Günther D, Pandit J, Rudel T, Brandt E, Meyer TF. Neisseria gonorrhoeae porin modifies the oxidative burst of human professional phagocytes. Infect Immun. 2000 Nov 68(11):6215-22. PMID: 11035728; PMCID: PMC97702
     
  • Müller A, Günther D, Brinkmann V, Hurwitz R, Meyer TF, Rudel T. Targeting of the pro-apoptotic VDAC-like porin (PorB) of Neisseria gonorrhoeae to mitochondria of infected cells. EMBO J. 2000 Oct 16;19(20):5332-43 PMID: 11032801; PMCID: PMC314008
     
  • Deane JA, Fraunholz M, Su V, Maier U-G, Martin W, Durnford DG, McFadden GI. Evidence for nucleomorph to host nucleus gene transfer: light-harvesting complex proteins from cryptomonads and chlorarachniophytes. Protist. 2000 Oct 151(3):239-52. PMID: 11079769
     
  • Thiede B, Siejak F, Dimmler C, Jungblut PR, Rudel T. A two dimensional electrophoresis database of a human Jurkat T-cell line. Electrophoresis. 2000 Jul 21(13):2713-20. PMID: 10949150
     
  • Lockhart PJ, Huson D, Maier U, Fraunholz MJ, Van De Peer Y, Barbrook AC, Howe CJ, Steel MA. How molecules evolve in eubacteria. Mol Biol Evol. 2000 May 17(5):835-8. PMID: 10779544
     
  • Maier UG, Fraunholz M, Zauner S, Penny S, Douglas S. A nucleomorph-encoded CbbX and the phylogeny of RuBisCo regulators. Mol Biol Evol. 2000 Apr 17(4):576-83. PMID: 10742049
     
  • Zauner S, Fraunholz M, Wastl J, Penny S, Beaton M, Cavalier-Smith T, Maier UG, Douglas S. Chloroplast protein and centrosomal genes, a tRNA intron, and odd telomeres in an unusually compact eukaryotic genome, the cryptomonad nucleomorph. Proc Natl Acad Sci U S A. 2000 Jan 4;97(1):200-5 PMID: 10618395; PMCID: PMC26640
     
  • Thiede B, Lamer S, Mattow J, Siejak F, Dimmler C, Rudel T, Jungblut PR. Analysis of missed cleavage sites, tryptophan oxidation and N-terminal pyroglutamylation after in-gel tryptic digestion. Rapid Commun Mass Spectrom. "2000;14(6):496-502 PMID: 10717661
     
  • Al-Younes HM, Rudel T, Meyer TF. Characterization and intracellular trafficking pattern of vacuoles containing Chlamydia pneumoniae in human epithelial cells. Cell Microbiol. 1999 Nov 1(3):237-47. PMID: 11207556
     
  • Rudel T. Caspase inhibitors in prevention of apoptosis. Herz. 1999 May 24(3):236-41. PMID: 10412648
     
  • Naumann M, Rudel T, Meyer TF. Host cell interactions and signalling with Neisseria gonorrhoeae. Curr Opin Microbiol. 1999 Feb 2(1):62-70. PMID: 10047561
     
  • Bauer FJ, Rudel T, Stein M, Meyer TF. Mutagenesis of the Neisseria gonorrhoeae porin reduces invasion in epithelial cells and enhances phagocyte responsiveness. Mol Microbiol. 1999 Feb 31(3):903-13. PMID: 10048033
     
  • Scheuerpflug I, Rudel T, Ryll R, Pandit J, Meyer TF. Roles of PilC and PilE proteins in pilus-mediated adherence of Neisseria gonorrhoeae and Neisseria meningitidis to human erythrocytes and endothelial and epithelial cells. Infect Immun. 1999 Feb 67(2):834-43. PMID: 9916098; PMCID: PMC96394
     
  • Müller A, Günther D, Düx F, Naumann M, Meyer TF, Rudel T. Neisserial porin (PorB) causes rapid calcium influx in target cells and induces apoptosis by the activation of cysteine proteases. EMBO J. 1999 Jan 15;18(2):339-52 PMID: 9889191; PMCID: PMC1171129
     
  • Wastl J, Fraunholz M, Zauner S, Douglas S, Maier UG. Ancient gene duplication and differential gene flow in plastid lineages: the GroEL/Cpn60 example. J Mol Evol. 1999 Jan 48(1):112-7. PMID: 9873083
     
  • Fraunholz MJ, Moerschel E, Maier UG. The chloroplast division protein FtsZ is encoded by a nucleomorph gene in cryptomonads. Mol Gen Genet. 1998 Nov 260(2-3):207-11. PMID: 9862473
     
  • Naumann M, Rudel T, Wieland B, Bartsch C, Meyer TF. Coordinate activation of activator protein 1 and inflammatory cytokines in response to Neisseria gonorrhoeae epithelial cell contact involves stress response kinases. J Exp Med 1998 Oct 5;188(7):1277-86 PMID: 9763607; PMCID: PMC2212490
     
  • Rudel T, Zenke FT, Chuang TH, Bokoch GM. p21-activated kinase (PAK) is required for Fas-induced JNK activation in Jurkat cells. J Immunol. 1998 Jan 1;160(1):7-11 PMID: 9551947
     
  • Mellies J, Rudel T, Meyer TF. Transcriptional regulation of pilC2 in Neisseria gonorrhoeae: response to oxygen availability and evidence for growth-phase regulation in Escherichia coli. Mol Gen Genet. 1997 Jul 255(3):285-93. PMID: 9268019
     
  • Rudel T, Bokoch GM. Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2. Science. 1997 Jun 6;276(5318):1571-4 PMID: 9171063
     
  • Fussenegger M, Rudel T, Barten R, Ryll R, Meyer TF. Transformation competence and type-4 pilus biogenesis in Neisseria gonorrhoeae--a Gene. Gene. 1997 Jun 11;192(1):125-34. PMID: 9224882
     
  • Ryll RR, Rudel T, Scheuerpflug I, Barten R, Meyer TF. PilC of Neisseria meningitidis is involved in class II pilus formation and restores pilus assembly, natural transformation competence and adherence to epithelial cells in PilC-deficient gonococci. Mol Microbiol. 1997 Mar 23(5):879-92. PMID: 9076726
     
  • Rudel T, Schmid A, Benz R, Kolb HA, Lang F, Meyer TF. Modulation of Neisseria porin (PorB) by cytosolic ATP/GTP of target cells: parallels between pathogen accommodation and mitochondrial endosymbiosis. Cell. 1996 May 3;85(3):391-402 PMID: 8616894
     
  • Kupsch EM, Aubel D, Gibbs CP, Kahrs AF, Rudel T, Meyer TF. Construction of Hermes shuttle vectors: a versatile system useful for genetic complementation of transformable and non-transformable Neisseria mutants. Mol Gen Genet. 1996 Mar 20;250(5):558-69 PMID: 8676859
     
  • Rudel T, Boxberger HJ, Meyer TF. Pilus biogenesis and epithelial cell adherence of Neisseria gonorrhoeae pilC double knock-out mutants. Mol Microbiol. 1995 Sep 17(6):1057-71. PMID: 8594326
     
  • Rudel T, Facius D, Barten R, Scheuerpflug I, Nonnenmacher E, Meyer TF. Role of pili and the phase-variable PilC protein in natural competence for transformation of Neisseria gonorrhoeae. Proc Natl Acad Sci U S A. 1995 Aug 15;92(17):7986-90 PMID: 7644525; PMCID: PMC41271
     
  • Rudel T, Scheurerpflug I, Meyer TF. Neisseria PilC protein identified as type-4 pilus tip-located adhesin. Nature. 1995 Jan 26;373(6512):357-9 PMID: 7830772
     
  • Rudel T, van Putten JP, Gibbs CP, Haas R, Meyer TF. Interaction of two variable proteins (PilE and PilC) required for pilus-mediated adherence of Neisseria gonorrhoeae to human epithelial cells. Mol Microbiol. 1992 Nov 6(22):3439-50. PMID: 1362447