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  • HEK-293T cells infected with Chlamydia trachomatis expressing chlamydial deubiquitinase Cdu1-FLAG
Chair of Microbiology

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Chlamydiae are sexually transmitted pathogens that can apparently survive in the human gut for a long time. Researchers from Würzburg and Berlin report this in the journal PLOS Pathogens.

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Sphingolipid expansion microscopy (ExM) of tenfold expanded cells infected with chlamydia. The bacterial membranes are marked green; the inner and outer membranes of the bacteria can be distinguished (c). Under (a) confocal laser scanning and under (b) structured illumination microscopy (SIM). Scale bars: 10 and 2 microns in the small white rectangles respectively.

For the first time ever, expansion microscopy allows the imaging of even the finest details of cell membranes. This offers new insights into bacterial and viral infection processes.

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