Functional Proteomics (Warscheid Lab)

Welcome to the Warscheid lab

At the Warscheid lab, mass spectrometric analysis is used to answer biological questions from the molecular to the cellular level. Central questions are the biogenesis of the proteome of mitochondria and peroxisomes and the integration of these vital organelles into larger signalling networks in yeast and human cells. In a complementary branch of research, we systematically investigate protein kinase- and protein phosphatase-dependent signalling networks to elucidate signalling processes involved in protection against mechanical stress.

Team

Publications

Research Focus

Mechanical Stress

Mitochondria in Health and Disease

Protein Import into Peroxisomes

News from the lab

Paper out: Regulation of Filamin C by Protein Phosphatase-1

A new study performed by Johannes Zimmermann and former lab mate Anja Schwäble from the lab of Bettina Warscheid together with Thomas Kokot from the lab of Maja Köhn investigates the role of protein phosphatase-1 (PP1) in skeletal muscle cells during mechanical stress.

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Start of installation of the new mass spectrometers

The installation of the new mass spectrometers in the laboratory began today with the Orbitrap Ascend. Over the next two weeks, the Orbitrap Ascend and Orbitrap Astral will be brought to high vacuum, tested, calibrated and connected to the liquid chromatography systems.

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