Functional Proteomics Toolbox. In our research, we use and develop high-end MS-based proteomics technologies together with a collection of advanced molecular biology and biochemical methods to study the various dynamic properties of proteins (e.g. abundance, interactions, PTMs, turnover, localization) on a system. broad scale. Key to our in-depth analysis of protein interaction and signaling networks, membrane protein assemblies, and dynamic organellar proteomes is the use of quantitative high-resolution MS technologies in combination with computational proteomics approaches and statistical data analysis.
