Center for Computational and Theoretical Biology

Chaitanya Gokhale (Prof. Dr.)

Prof. Dr. Chaitanya Gokhale

Professor for Theoretical Biology
Center for Computational and Theoretical Biology (CCTB)
Klara-Oppenheimer-Weg 32
Campus Hubland Nord
97074 Würzburg
Germany
Gebäude: 32
Raum: L8
Telefon: +49 931 31-84126
ORCID: https://orcid.org/0000-0002-5749-3665

https://tecoevo.github.io/

 

Hello! My name is Chaitanya and I am heading the group on Theoretical Biology at the CCTB. 

You can learn more about me and my research in the university's online magazine: From Cells to Societies

Research in my group spans levels of organization - from subcellular entities to societies. I am interested in elucidating the associations and interactions that power the emergent complexity at multiple scales. My focus is on eco-evolutionary processes within and between the valuable but amorphous organization of hierarchies of organization. My group members utilize the toolbox of theoretical biology while simultaneously developing it further. With "Insight preceding application" (Max Planck), we then eventually deploy our knowledge into action via translational programs.

  • since 2023: Professor
    Center for Computational and Theoretical Biology (CCTB), University of Würzburg, Würzburg, Germany
     
  • since 2016: Group leader
    Max Planck Institute for Evolutionary Biology, Plön, Germany
     
  • 2014-2016: Post doctoral researcher
    New Zealand Institute for Advanced Study, Massey University, Auckland, New Zealand
     
  • 2011-2014: Post doctoral researcher
    Max Planck Institute for Evolutionary Biology, Plön, Germany
     
  • 2011: PhD in Natural Sciences

    Christian Albrechts University of Kiel, Max Planck Institute for Evolutionary Biology
    Thesis: "Evolutionary dynamics on multi-dimensional fitness landscapes"

  • 2008: Master of Science in Bioinformatics
    Sikkim Manipal University of Health Medical and Technological Sciences, National Center for Biological Science, Bangalore, India
    Thesis: "Ab initio calculations in the HGPRT active site and the analysis of select mutations"

  • 2005: Bachelor of Science in Zoology and Biotechnology
    Fergusson College, Pune, India

2025[ to top ]
  • On multiple infections by parasites with complex life cycles. Nguyen, Phuong L.; Gokhale, Chaitanya S. In Oikos, p. e10493. 2025.
  • Compartment model of strategy-dependent time delays in replicator dynamics. Fic, Małgorzata; Bastian, Frank; Miȩkisz, Jacek; Gokhale, Chaitanya S. In Journal of Theoretical Biology, 601, p. 112044. 2025.
2024[ to top ]
  • Catalysing cooperation: the power of collective beliefs in structured populations. Fic, Małgorzata; Gokhale, Chaitanya S. In npj Complex, 1(1), p. 6. 2024.
  • Effects of time spent in pregnancy or brooding on immunocompetence. Revathi Venkateswaran, Vandana; Gokhale, Chaitanya S.; Mangel, Marc; Eliassen, Sigrunn. In Ecology and Evolution, 14(1), p. e10764. 2024.
2023[ to top ]
  • Optimizing crop rotations via Parrondo’s paradox for sustainable agriculture. Gokhale, Chaitanya S.; Sharma, Nikhil. In R. Soc. Open Sci., 10(5), p. 221401. 2023.
  • Theoretical assessment of persistence and adaptation in weeds with complex life cycles. Lauenroth, Dana; Gokhale, Chaitanya S. In Nat. Plants, 9(8), pp. 1267–1279. 2023.
  • Antibiotic-mediated interactions underlying microbial diversity. Athreya, Gaurav S.; Gokhale, Chaitanya S.; Verma, Prateek. In bioRxiv, p. 2023.02.15.528676. 2023.
  • The Effect of Mating Complexity on Gene Drive Dynamics. Verma, Prateek; Reeves, R Guy; Simon, Samson; Otto, Mathias; Gokhale, Chaitanya S. In The American Naturalist, 201(1), pp. E1-E22. 2023.
  • The Effect of Mating Complexity on Gene Drive Dynamics. Verma, Prateek; Reeves, R Guy; Simon, Samson; Otto, Mathias; Gokhale, Chaitanya S. In Am. Nat., 201(1), pp. E1-E22. 2023.
  • Theoretical assessment of persistence and adaptation in weeds with complex life cycles. Lauenroth, Dana; Gokhale, Chaitanya S. In bioRxiv, p. 2022.08.12.503772. 2023.
  • Optimizing crop rotations via Parrondo’s paradox for sustainable agriculture. Gokhale, Chaitanya S.; Sharma, Nikhil. In Royal Society Open Science, 10(5), p. 221401. 2023.
  • Ecological Drivers of Community Cohesion. Gokhale, Chaitanya S.; Velasque, Mariana; Denton, Jai A. In mSystems, 8(1), pp. e00929–22. 2023.
2022[ to top ]
  • Impact of female mate copying on male morph dynamics. Patil, Srishti; Nöbel, Sabine; Gokhale, Chaitanya S. In bioRxiv, p. 2022.09.13.507757. 2022.
  • Collective narratives catalyse cooperation. Gokhale, Chaitanya S.; Bulbulia, Joseph; Frean, Marcus. In Humanities and Social Sciences Communications, 9(1), p. 85. 2022.
  • Evolution of reproductive strategies in incipient multicellularity. Gao, Yuanxiao; Pichugin, Yuriy; Gokhale, Chaitanya S.; Traulsen, Arne. In Journal of the Royal Society Interface, 19(188), p. 20210716. 2022.
  • The Covid-19 Pandemic: Basic Insights from Basic Mathematical Models. Traulsen, Arne; Gokhale, Chaitanya S.; Shah, Saumil; Uecker, Hildegard. In NOVA ACTA LEOPOLDINA. 2022.
  • Parasitoid pressures and silence evolution. Suswaram, Megha R.; Yeakel, Justin D.; Gokhale, Chaitanya S. In bioRxiv, p. 2022.08.12.503800. 2022.
2021[ to top ]
  • Consequences of combining sex‐specific traits. Venkateswaran, Vandana Revathi; Roth, Olivia; Gokhale, Chaitanya S. In Evolution, 75(6), pp. 1274–1287. 2021.
  • How sequence populations persist inside bacterial genomes. Park, Hye Jin; Gokhale, Chaitanya S; Bertels, Frederic. In Genetics, 217(4), p. iyab027. 2021.
  • Memory shapes microbial populations. Gokhale, Chaitanya S.; Giaimo, Stefano; Remigi, Philippe. In PLoS Computational Biology, 17(10), p. e1009431. 2021.
  • A common gene drive language eases regulatory process and eco-evolutionary extensions. Verma, Prateek; Reeves, R. Guy; Gokhale, Chaitanya S. In BMC Ecology and Evolution, 21(1), p. 156. 2021.
  • On the fitness of informative cues in complex environments. Mafessoni, Fabrizio; Lachmann, Michael; Gokhale, Chaitanya S. In Journal of Theoretical Biology, 527, p. 110819. 2021.
2020[ to top ]
  • The Art of Theoretical Biology. Schenk, Hanna; Gokhale, Chaitanya; Traulsen, Arne. ["Franziska Matthäus", "Sebastian Matthäus", "Sarah Harris", "Thomas Hillen"] (eds.), pp. 16–17. Springer International Publishing, Cham, 2020.
  • Eco-evolutionary agriculture: Host-pathogen dynamics in crop rotations. Bargués-Ribera, Maria; Gokhale, Chaitanya S. In PLoS Comput. Biol., 16(1), M. Bargués-Ribera; C. S. Gokhale (eds.). Center for Computational and Theoretical Biology (CCTB), 2020.
  • Eco-evolutionary agriculture: Host-pathogen dynamics in crop rotations. Bargués-Ribera, Maria; Gokhale, Chaitanya S. In PLoS Computational Biology, 16(1), p. e1007546. 2020.
  • Synthetic Symbiosis under Environmental Disturbances. Denton, Jai A.; Gokhale, Chaitanya S. In mSystems, 5(3), pp. e00187–20. 2020.
  • Advances in Dynamic Games, Games of Conflict, Evolutionary Games, Economic Games, and Games Involving Common Interest. Gokhale, Chaitanya S.; Park, Hye Jin. In Annals of the International Society of Dynamic Games, pp. 187–200. 2020.
  • The Art of Theoretical Biology. Schenk, Hanna; Gokhale, Chaitanya; Traulsen, Arne. pp. 16–17. Springer International Publishing, Cham, 2020.
2019[ to top ]
  • On the innovation and evolution of predatory tactics. Gokhale, Chaitanya S.; Wignall, Anne E. In bioRxiv, p. 530238. 2019.
  • Evolutionary dynamics of complex multiple games. Venkateswaran, Vandana Revathi; Gokhale, Chaitanya S. In Proceedings of the Royal Society B, 286(1905), p. 20190900. 2019.
  • Synthetic Mutualism and the Intervention Dilemma. Denton, Jai A.; Gokhale, Chaitanya S. In Life, 9(1), p. 15. 2019.
  • Eco-evolutionary dynamics of Plasmodium genotypes under mass drug administration. Bargués-Ribera, Maria; Reeves, R. Guy; Gokhale, Chaitanya S. In bioRxiv, p. 818039. 2019.
  • Ecological feedback on diffusion dynamics. Park, Hye Jin; Gokhale, Chaitanya S. In Royal Society Open Science, 6(2), p. 181273. 2019.
2018[ to top ]
  • Cellular hysteresis as a principle to maximize the efficacy of antibiotic therapy. Roemhild, Roderich; Gokhale, Chaitanya S.; Dirksen, Philipp; Blake, Christopher; Rosenstiel, Philip; Traulsen, Arne; Andersson, Dan I.; Schulenburg, Hinrich. In Proceedings of the National Academy of Sciences, 115(39), pp. 9767–9772. 2018.
  • Disentangling eco-evolutionary effects on trait fixation. Czuppon, Peter; Gokhale, Chaitanya S. In Theoretical Population Biology, 124, pp. 93–107. 2018.
2017[ to top ]
  • Chaotic provinces in the kingdom of the Red Queen. Schenk, Hanna; Traulsen, Arne; Gokhale, Chaitanya S. In Journal of Theoretical Biology, 431, pp. 1–10. 2017.
  • Discovering Complete Quasispecies in Bacterial Genomes. Bertels, Frederic; Gokhale, Chaitanya S; Traulsen, Arne. In Genetics, 206(4), pp. 2149–2157. 2017.
  • Spatio-temporal control of mutualism in legumes helps spread symbiotic nitrogen fixation. Daubech, Benoit; Remigi, Philippe; Moura, Ginaini Doin de; Marchetti, Marta; Pouzet, Cécile; Auriac, Marie-Christine; Gokhale, Chaitanya S; Masson-Boivin, Catherine; Capela, Delphine. In eLife, 6, p. e28683. 2017.
  • Unravelling the complexity and redundancy of carbon catabolic repression in Pseudomonas fluorescens SBW25. Liu, Yunhao; Gokhale, Chaitanya S.; Rainey, Paul B.; Zhang, Xue‐Xian. In Molecular Microbiology, 105(4), pp. 589–605. 2017.
  • Social dilemma in the external immune system of the red flour beetle? It is a matter of time. Gokhale, Chaitanya S.; Traulsen, Arne; Joop, Gerrit. In Ecology and Evolution, 7(17), pp. 6758–6765. 2017.
2016[ to top ]
  • Eco-evolutionary dynamics of social dilemmas. Gokhale, Chaitanya S.; Hauert, Christoph. In Theoretical Population Biology, 111, pp. 28–42. 2016.
  • Host–parasite coevolution: why changing population size matters. Papkou, Andrei; Gokhale, Chaitanya S.; Traulsen, Arne; Schulenburg, Hinrich. In Zoology, 119(4), pp. 330–338. 2016.
2015[ to top ]
  • Host-parasite coevolution in populations of constant and variable size. Song, Yixian; Gokhale, Chaitanya S; Papkou, Andrei; Schulenburg, Hinrich; Traulsen, Arne. In BMC Evolutionary Biology, 15(1), p. 212. 2015.
  • Repeatability of evolution on epistatic landscapes. Bauer, Benedikt; Gokhale, Chaitanya S. In Scientific Reports, 5(1), p. 9607. 2015.
  • Modes of migration and multilevel selection in evolutionary multiplayer games. Pichugin, Yuriy; Gokhale, Chaitanya S.; Garcia, Julián; Traulsen, Arne; Rainey, Paul B. In Journal of Theoretical Biology, 387, pp. 144–153. 2015.
2014[ to top ]
  • Evolutionary Multiplayer Games. Gokhale, Chaitanya S.; Traulsen, Arne. In Dynamic Games and Applications, 4(4), pp. 468–488. 2014.
  • Evolutionary Multiplayer Games. Gokhale, Chaitanya S.; Traulsen, Arne. In Dyn. Games Appl., 4(4), C. S. Gokhale; A. Traulsen (eds.), pp. 468–488. Center for Computational and Theoretical Biology (CCTB), 2014.
  • Dynamics of a combined medea-underdominant population transformation system. Gokhale, Chaitanya S; Reeves, Richard Guy; Reed, Floyd A. In BMC Evolutionary Biology, 14(1), p. 98. 2014.
2013[ to top ]
  • Dynamic Properties of Evolutionary Multi-player Games in Finite Populations. Wu, Bin; Traulsen, Arne; Gokhale, Chaitanya. In Games, 4(2), pp. 182–199. Center for Computational and Theoretical Biology (CCTB), 2013.
  • Interpretations arising from Wrightian and Malthusian fitness under strong frequency dependent selection. Wu, Bin; Gokhale, Chaitanya S.; Veelen, Matthijs; Wang, Long; Traulsen, Arne. In Ecology and Evolution, 3(5), pp. 1276–1280. 2013.
  • Lotka–Volterra dynamics kills the Red Queen: population size fluctuations and associated stochasticity dramatically change host-parasite coevolution. Gokhale, Chaitanya S; Papkou, Andrei; Traulsen, Arne; Schulenburg, Hinrich. In BMC Evolutionary Biology, 13(1), p. 254. 2013.
2012[ to top ]
  • Mutualism and evolutionary multiplayer games: revisiting the Red King. Gokhale, Chaitanya S.; Traulsen, Arne. In Proceedings of the Royal Society B: Biological Sciences, 279(1747), pp. 4611–4616. 2012.
  • On equilibrium properties of evolutionary multi-player games with random payoff matrices. Han, The Anh; Traulsen, Arne; Gokhale, Chaitanya S. In Theoretical Population Biology, 81(4), pp. 264–272. 2012.
  • How small are small mutation rates?. Wu, Bin; Gokhale, Chaitanya S.; Wang, Long; Traulsen, Arne. In Journal of Mathematical Biology, 64(5), pp. 803–827. 2012.
2011[ to top ]
  • Strategy abundance in evolutionary many-player games with multiple strategies. Gokhale, Chaitanya S.; Traulsen, Arne. In Journal of Theoretical Biology, 283(1), pp. 180–191. 2011.
2010[ to top ]
  • Evolutionary games in the multiverse. Gokhale, Chaitanya S.; Traulsen, Arne. In Proceedings of the National Academy of Sciences, 107(12), pp. 5500–5504. 2010.
  • Stochastic slowdown in evolutionary processes. Altrock, Philipp M.; Gokhale, Chaitanya S.; Traulsen, Arne. In Physical Review E, 82(1), p. 011925. 2010.
2009[ to top ]
  • MtSNPscore: a combined evidence approach for assessing cumulative impact of mitochondrial variations in disease. Bhardwaj, Anshu; Mukerji, Mitali; Sharma, Shipra; Paul, Jinny; Gokhale, Chaitanya S.; Srivastava, Achal K.; Tiwari, Shrish. In BMC Bioinform., 10(S-8), p. 7. 2009.
  • The pace of evolution across fitness valleys. Gokhale, Chaitanya S.; Iwasa, Yoh; Nowak, Martin A.; Traulsen, Arne. In Journal of Theoretical Biology, 259(3), pp. 613–620. 2009.
  • MtSNPscore: a combined evidence approach for assessing cumulative impact of mitochondrial variations in disease. Bhardwaj, Anshu; Mukerji, Mitali; Sharma, Shipra; Paul, Jinny; Gokhale, Chaitanya S; Srivastava, Achal K; Tiwari, Shrish. In BMC Bioinformatics, 10(Suppl 8), p. S7. 2009.