AG Häring | Publikationen
2023[ to top ]
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How do molecular motors fold the genome?Science, 382(6671): 646–648.
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2022[ to top ]
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A hold-and-feed mechanism drives directional DNA loop extrusion by condensinScience, 376(6597): 1087–1094.
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2020[ to top ]
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Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanismNature Structural and Molecular Biology, 27(8): 743–751.
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The condensin holocomplex cycles dynamically between open and collapsed statesNature Structural and Molecular Biology. https://doi.org/10.1038/s41594-020-0508-3.
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DNA-loop extruding condensin complexes can traverse one anotherNature, 579(7799): 438–442.
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Structural insights into DNA loop extrusion by SMC protein complexesCurrent Opinion in Structural Biology, 65: 102–109.
2019[ to top ]
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Twist to disentangleNature Structural and Molecular Biology, 26(4): 252–253.
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Distinct Roles for Condensin’s Two ATPase Sites in Chromosome CondensationMolecular Cell, 76(5): 724–737.e5.
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Structural Basis of an Asymmetric Condensin ATPase CycleMolecular Cell, 74(6): 1175–1188.
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Solution structure and flexibility of the condensin HEAT-repeat subunit Ycg1J Biol Chem, 294(37): 13822–13829.
2018[ to top ]
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Control of mitotic chromosome condensation by the fission yeast transcription factor Zas1Journal of Cell Biology, 217(7): 2383–2401.
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Structural basis for Scc3-dependent cohesin recruitment to chromatinELife, 7. https://doi.org/10.7554/elife.38356.
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Towards a Unified Model of SMC Complex FunctionCurrent Biology, 28(21): R1266-R1281.
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Real-time imaging of DNA loop extrusion by condensinScience, 360(6384): 102–105.
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Condensin controls cellular RNA levels through the accurate segregation of chromosomes instead of directly regulating transcriptionELife, 7. https://doi.org/10.7554/elife.38517.
2017[ to top ]
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Two independent modes of chromatin organization revealed by cohesin removalNature, 551(7678): 51–56.
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Structural Basis for a Safety-Belt Mechanism That Anchors Condensin to ChromosomesCell, 171(3): 588–600.e24.
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Real-time detection of condensin-driven DNA compaction reveals a multistep binding mechanismThe EMBO Journal, 36(23): 3448–3457.
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The condensin complex is a mechanochemical motor that translocates along DNAScience, 358(6363): 672–676.
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A Protocol for Measuring Mitotic Chromosome Condensation Quantitatively in Fission Yeast CellsMethods Mol Biol, 1515: 245–255.
2016[ to top ]
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Condensin Smc2-Smc4 Dimers Are Flexible and DynamicCell Reports, 14(8): 1813–1818.
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SnapShot: SMC Protein Complexes Part ICell, 164(1-2): 326–326.e1.
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Structure of the Pds5-Scc1 Complex and Implications for Cohesin FunctionCell Reports, 14(9): 2116–2126.
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Nucleosome eviction in mitosis assists condensin loading and chromosome condensationThe EMBO Journal, 35(14): 1565–1581.
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SnapShot: SMC Protein Complexes Part IICell, 164(4): 818–818.e1.
2015[ to top ]
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Shaping mitotic chromosomes: From classical concepts to molecular mechanismsBioessays, 37(7): 755–66.
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Control of chromosome interactions by condensin complexesCurrent Opinion in Cell Biology, 34: 94–100.
2014[ to top ]
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Integration of biological data by kernels on graph nodes allows prediction of new genes involved in mitotic chromosome condensation (D. G. Drubin, Ed.)Molecular Biology of the Cell, 25(16): 2522–2536.
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Association of condensin with chromosomes depends on DNA binding by its HEAT-repeat subunitsNature Structural & Molecular Biology, 21(6): 560–568.
2013[ to top ]
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Understanding chromatin and chromosomes: from static views to dynamic thinkingEMBO Reports, 14(2): 109–111.
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Quantitative analysis of chromosome condensation in fission yeastMol Cell Biol, 33(5): 984–98.
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Condensin: crafting the chromosome landscapeChromosoma, 122(3): 175–190.
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Entrapment of Chromosomes by Condensin Rings Prevents Their Breakage during CytokinesisDevelopmental Cell, 27(4): 469–478.
2012[ to top ]
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Cohesin in determining chromosome architectureExperimental Cell Research, 318(12): 1386–1393.
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2011[ to top ]
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A FlAsH-based cross-linker to study protein interactions in living cellsAngew Chem Int Ed Engl, 50(52): 12655–8.
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Condensin engages chromatinChembiochem, 12(16): 2399–401.
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Deciphering condensin action during chromosome segregationTrends in Cell Biology, 21(9): 552–559.
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Condensin structures chromosomal DNA through topological linksNature Structural and Molecular Biology, 18(8): 894–901.
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2010[ to top ]
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A positively charged channel within the Smc1/Smc3 hinge required for sister chromatid cohesionThe EMBO Journal, 30(2): 364–378.
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A New Cohesive Team to Mediate DNA LoopingCell Stem Cell, 7(4): 424–426.
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2009[ to top ]
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Cohesin: Its Roles and MechanismsAnnual Review of Genetics, 43(1): 525–558.
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Foreword: the many fascinating functions of SMC protein complexesChromosome Research, 17(2): 127–129.
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2008[ to top ]
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The cohesin ring concatenates sister DNA moleculesNature, 454(7202): 297–301.
2006[ to top ]
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Cohesin’s ATPase Activity Is Stimulated by the C-Terminal Winged-Helix Domain of Its Kleisin SubunitCurrent Biology, 16(20): 1998–2008.
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2005[ to top ]
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THE STRUCTURE AND FUNCTION OF SMC AND KLEISIN COMPLEXESAnnual Review of Biochemistry, 74(1): 595–648.
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2004[ to top ]
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Structure and Stability of Cohesin’s Smc1-Kleisin InteractionMolecular Cell, 15(6): 951–964.
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2003[ to top ]
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Building and breaking bridges between sister chromatidsBioessays, 25(12): 1178–91.
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ATP Hydrolysis Is Required for Cohesin’s Association with ChromosomesCurrent Biology, 13(22): 1941–1953.
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Chromosomal Cohesin Forms a RingCell, 112(6): 765–777.
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2002[ to top ]
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Molecular Architecture of SMC Proteins and the Yeast Cohesin ComplexMolecular Cell, 9(4): 773–788.
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Eco1 Is a Novel Acetyltransferase that Can Acetylate Proteins Involved in CohesionCurrent Biology, 12(4): 323–328.
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2000[ to top ]
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Analysis of telomerase catalytic subunit mutants in vivo and in vitro in Schizosaccharomyces pombeProc Natl Acad Sci U S A, 97(12): 6367–72.